ID   A0A067C3E5_SAPPC        Unreviewed;       933 AA.
AC   A0A067C3E5;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Lipoxygenase domain-containing protein {ECO:0000259|PROSITE:PS51393};
GN   ORFNames=SPRG_09114 {ECO:0000313|EMBL:KDO25284.1};
OS   Saprolegnia parasitica (strain CBS 223.65).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO25284.1, ECO:0000313|Proteomes:UP000030745};
RN   [1] {ECO:0000313|EMBL:KDO25284.1, ECO:0000313|Proteomes:UP000030745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO25284.1,
RC   ECO:0000313|Proteomes:UP000030745};
RX   PubMed=23785293;
RA   Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA   van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA   Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA   Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA   Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA   Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA   Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA   Russ C., Tyler B.M., van West P.;
RT   "Distinctive expansion of potential virulence genes in the genome of the
RT   oomycete fish pathogen Saprolegnia parasitica.";
RL   PLoS Genet. 9:E1003272-E1003272(2013).
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DR   EMBL; KK583233; KDO25284.1; -; Genomic_DNA.
DR   RefSeq; XP_012203942.1; XM_012348552.1.
DR   AlphaFoldDB; A0A067C3E5; -.
DR   STRING; 695850.A0A067C3E5; -.
DR   EnsemblProtists; KDO25284; KDO25284; SPRG_09114.
DR   GeneID; 24131307; -.
DR   KEGG; spar:SPRG_09114; -.
DR   VEuPathDB; FungiDB:SPRG_09114; -.
DR   OMA; LETEAFH; -.
DR   OrthoDB; 45595at2759; -.
DR   Proteomes; UP000030745; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   CDD; cd00302; cytochrome_P450; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   InterPro; IPR013819; LipOase_C.
DR   InterPro; IPR036226; LipOase_C_sf.
DR   PANTHER; PTHR24286; CYTOCHROME P450 26; 1.
DR   PANTHER; PTHR24286:SF194; CYTOCHROME P450 26A1; 1.
DR   Pfam; PF00305; Lipoxygenase; 1.
DR   Pfam; PF00067; p450; 1.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   SUPFAM; SSF48484; Lipoxigenase; 1.
DR   PROSITE; PS51393; LIPOXYGENASE_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030745}.
FT   DOMAIN          648..800
FT                   /note="Lipoxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51393"
SQ   SEQUENCE   933 AA;  103682 MW;  25418776DE685C71 CRC64;
     MGNEASTVHA DGAATDLPAS QRAMNILKMI EFSKDPRAGM LESRDQYGDL FLLESHLVSE
     KIAGFCGPEL LAAFDDKLRD GSIVREGAFP PGIVALLGAI MPTIDGEEHH ARKAAALEAF
     TPARLDLYAP LVREIVQAEH ASWAARGGAI SLACLTREMV FRIFLKVLYG VERHDANKFR
     KRPDPHGVSC RTQILDELIR PAIADARARA ATKTPAPSVI DCLVTNGKMA SDVLETEAFH
     FLFAGFGGVA CLATNILTAV ATHPSARKDL LDARAEYVTK YDGEARWAHF HDLGYVNLFI
     LEVKRFYVAG PTAVFGRAKT DLEIPTKNGV YKLPKGCLAA AGLEATNRHP DVWTDPNLFN
     PNRFRDLGHV RTTKPHAFCP HAFGALSHRR CAGEDLTTLI LQSTIVSLFD FVWQMVPNQD
     YKLAVGVSTP TPVGQLMAVG FHRRTDDAAE IIGTVGSNAD WKFLNLPESK ELALWDRPYA
     NQILSIPQHQ KTLPKITLIQ THIEIATEDE DWPSQPWIEI QQSNFLRDYA PFVDNFELTW
     LPGEDMERYV MSKVGHMWPR VNVHWNDRYS DRALELLAFN GFGQHLLMKL PEAHDDGSYY
     GICLGFVKGL EVRPGYAKYG ADVYFTAKGN VTKIVRGDIT SRPGDAGWEY AKLCFRGSLQ
     TKVTAVDHLL GIHATVANIM VIANREKLPP THPLRRLIKP FTFRSVAINY GAGRALFWPK
     GMLQRAYALT DKGMKQTWDF GLANFKYETF PEHKARQNID TTTLPFHEDG MDYWQICRSF
     VSNYVDLYFK SEDALQNDTD NLKDFVAHFI FLVSSMHNHL GTIAEYVSDP AFCPSAWVEG
     ELAGRPGTGV RLALIMTATG FAQPAITEDF SHIMLDDAGK AVCQAFTAAV TAQIAVVDAR
     NATRVQPYQS FNPKTMEMAV TVAVDATGSS KRR
//