ID   A0A067C8J3_SAPPC        Unreviewed;       646 AA.
AC   A0A067C8J3;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN   ORFNames=SPRG_08103 {ECO:0000313|EMBL:KDO26813.1};
OS   Saprolegnia parasitica (strain CBS 223.65).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO26813.1, ECO:0000313|Proteomes:UP000030745};
RN   [1] {ECO:0000313|EMBL:KDO26813.1, ECO:0000313|Proteomes:UP000030745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO26813.1,
RC   ECO:0000313|Proteomes:UP000030745};
RX   PubMed=23785293;
RA   Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA   van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA   Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA   Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA   Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA   Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA   Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA   Russ C., Tyler B.M., van West P.;
RT   "Distinctive expansion of potential virulence genes in the genome of the
RT   oomycete fish pathogen Saprolegnia parasitica.";
RL   PLoS Genet. 9:E1003272-E1003272(2013).
CC   -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
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DR   EMBL; KK583221; KDO26813.1; -; Genomic_DNA.
DR   RefSeq; XP_012202461.1; XM_012347071.1.
DR   AlphaFoldDB; A0A067C8J3; -.
DR   STRING; 695850.A0A067C8J3; -.
DR   EnsemblProtists; KDO26813; KDO26813; SPRG_08103.
DR   GeneID; 24130340; -.
DR   KEGG; spar:SPRG_08103; -.
DR   VEuPathDB; FungiDB:SPRG_08103; -.
DR   OMA; HILVMRR; -.
DR   OrthoDB; 1429709at2759; -.
DR   Proteomes; UP000030745; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR   InterPro; IPR000542; Carn_acyl_trans.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR039551; Cho/carn_acyl_trans.
DR   InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR   PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR22589:SF29; MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF00755; Carn_acyltransf; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR   PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000256|RuleBase:RU003801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT   DOMAIN          19..583
FT                   /note="Choline/carnitine acyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00755"
FT   ACT_SITE        306
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ   SEQUENCE   646 AA;  72477 MW;  5699C65CF8117ED2 CRC64;
     MGSSMKPTTF AGQASLPKLP IPDLQETIAN YLRTVSVLQS PEAHAATRAT AEAFLATDGP
     TLQAKLQAYA ADKNSFIEDF WYEAYFNYKE SVVLNVNPFF VLEDDPTPTR AKQIPRASSL
     ILSSLKFIHA LRRETLPPDV VRKTPLCMNQ FRMLFGATRL PTREKDHVKV APDAKHIVVL
     CRNQFYWFDV NLRAIRANAR QCSDDHIADS AVGVFTTEHR VEWARLRTEL QAENAATLDM
     IDRALFLVCL DHTSPPTPSD FAATMLHGTY ETSSHNRQVG SCMNRWYDKL QIIVCENGVA
     GVNFEHSVVD GHTVLRFVSD VFTDTVIRFA QSISGTTQCF LESAYRPPSE SLYMTPHKLE
     WQLSRSLQLS VRYAEARLSD LICQNEVKVL EFRNYGKRFI VKHKCSPDAF VQVAFLAAYY
     MQYGTAVNQY EPAMTKRFLH GRTEAIRSMT PETFAFIELF CGGNGNELQQ LNALRKATAS
     HSEVVKRSAG GNGIERHLYA LQQIASLNQL PEAALFKDAA WRTLGRSVIS TSNCGNPSLR
     LFGFGPVVPE GFGIGYIIKD DAIQFCAASK HRQTQRFLDT LKEYLLLVHA LLEKEDALLF
     PNRAKLASSK TEHRDSDYEF SFFDSGAPVP ASPKINPTPL IGKALF
//