ID A0A067CDF6_SAPPC Unreviewed; 717 AA.
AC A0A067CDF6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=5'-Nucleotidase C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_19994 {ECO:0000313|EMBL:KDO28784.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO28784.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO28784.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO28784.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SIMILARITY: Belongs to the 5'-nucleotidase family.
CC {ECO:0000256|ARBA:ARBA00006654, ECO:0000256|RuleBase:RU362119}.
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DR EMBL; KK583209; KDO28784.1; -; Genomic_DNA.
DR RefSeq; XP_012200524.1; XM_012345134.1.
DR AlphaFoldDB; A0A067CDF6; -.
DR STRING; 695850.A0A067CDF6; -.
DR EnsemblProtists; KDO28784; KDO28784; SPRG_19994.
DR GeneID; 24141237; -.
DR KEGG; spar:SPRG_19994; -.
DR VEuPathDB; FungiDB:SPRG_19994; -.
DR OMA; YTIAMVS; -.
DR OrthoDB; 295866at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR InterPro; IPR008334; 5'-Nucleotdase_C.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR006179; 5_nucleotidase/apyrase.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR11575:SF48; 5' NUCLEOTIDASE, ECTO-LIKE; 1.
DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR Pfam; PF02872; 5_nucleotid_C; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR01607; APYRASEFAMLY.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU362119};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362119};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Signal {ECO:0000256|RuleBase:RU362119}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU362119"
FT CHAIN 22..717
FT /note="5'-Nucleotidase C-terminal domain-containing
FT protein"
FT /evidence="ECO:0000256|RuleBase:RU362119"
FT /id="PRO_5001634401"
FT DOMAIN 22..244
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 324..429
FT /note="5'-Nucleotidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02872"
SQ SEQUENCE 717 AA; 78484 MW; BD83C9D55C7FD2FC CRC64;
MVATISKLLL LLGATATAVV GDCGTARAPT AHFQVLSYND VYEMKNESDA AQYGVLVGGP
SRVIPVAQKL RKNFANSLII FAGDTMSPSL WSGQFKGLQM IEAHNAIGVD FACLGNHEFD
FGIDAFLNVS AASKFPWLNI NAYEVATKQL LRGTQKYATK EFNSATMGKI KIGAFGVMYD
MQDATTGMYW TDPIAASKDA VKYLREVEKV DMVIALTHQF LDDDNRFSQQ VKGIDMIYGG
HDHTAMLQSN FGTPYLKSDL NFRSIWVSDI KYYGPLTEGK NKYAPFTKMS HKNLQITNEM
PSDPAFDAVI ATYDAKINEL FKRKAYYKKV TVDVGYMNAG GIRTDMVWPA GPFSLGDLIS
WSPFGNMIAV ISTDGASFKK FLASQLAPTC NQGTAALNGF YPQISGVKVT YKCSGKGMGA
ITSLKWDDNK NGKSGDIKDA DSVNMSLSTY MKGLFDDALN STAKYVIDAN EATRIDLVLE
TYTKVKEGVV CPNLEGRSSI SFNSSRSHAA LKDLAQTPRE AGNLLAHTVA DANDSDFICH
DAAAMTRIKA ARHPCPPGGP LELKMNEDKT EETKVFRSTQ ADAPTHAASL AWHTTKKLGG
TWALTPTRLM GLDSLHRRQL RRLLGIFHRH TLADVALYDR CNSIPLSEIV THQRWRLLEH
VLGVKDDAPA NICRRPLLSR VQSAPFCRPC QDRVANCLAP RPPVVDAASV AGVSQAA
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