ID A0A067CZT5_SAPPC Unreviewed; 1044 AA.
AC A0A067CZT5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=BK channel {ECO:0000256|ARBA:ARBA00029579};
GN ORFNames=SPRG_00826 {ECO:0000313|EMBL:KDO34765.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO34765.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO34765.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO34765.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KK583190; KDO34765.1; -; Genomic_DNA.
DR RefSeq; XP_012194432.1; XM_012339042.1.
DR AlphaFoldDB; A0A067CZT5; -.
DR STRING; 695850.A0A067CZT5; -.
DR EnsemblProtists; KDO34765; KDO34765; SPRG_00826.
DR GeneID; 24123453; -.
DR KEGG; spar:SPRG_00826; -.
DR VEuPathDB; FungiDB:SPRG_00826; -.
DR OMA; MMNDLNR; -.
DR OrthoDB; 67982at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 42..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 496..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..280
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 428..517
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 618..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..669
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..728
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1044 AA; 117123 MW; F5C9BD9626794CC3 CRC64;
MTAVRRKHGG ASWRSWRQQL IKDRMRGESF QRWAARNMDN SLFASLLDIV QVILGVFVTL
LYFQKNWVTW DTSMDGPVLR VVHAVFGTLF LLDYLLRLYA ADNMETYAFS PLAMIELVSI
PSQFVEVLFS EAQNRDNNIL FGAMKCLRPF RCLRCFRLLA FAKTARTRET GMLFFAVLSI
IICFGAVQQA MEACFCNDLP GLDPSNCSVV DRNTTGHCQD MEIYNAMYFV VITIATLGYG
DIAPKSTYGR IIVIVLIIAS TVLLPLQIST LSDVLNRDTE YDKAYTARRE QSPHVLICGE
VTSGALDFFL RQFLHPNNLN WKDKVVILCP SLPSHNLKRV LLNAAYEQRV MYLQGSAMLD
ADLKRASAAT ARLCFVLTNQ QARDADRSDT SSNFITISLR RFNKHLPIFV QVLKTDNIRH
VHLSGANNIV CLDQLKLGIL ARSCVLPGVS AFVCSILFAF RPFRGVDRSH VWASDFLRGC
SNDVYDVRVP RFLDGLVSFA FLAYVLFQEF GIVPIAMGHN DEYRLFPAKT RVRCDYKVYI
LSTSPDCSRR VGALSLVLLQ KYQTMLDNFD EITRAWNKHS FTSKLATRVQ QSSRRLLLTR
TTHRTSLVDS SFYSIKSNGR ASEADSDASH RSSIVVPCTT ETDVPTNGGD GATQDATEPF
VSAAPQPTSF QPLPKVIEGD DESSEKMPLP SQPHPAKRLP PLNVANSATP PPDASATQVV
VQQDKNTRSN SQLSLDYLSF LSTRVPDDLE DHILLCGMPN MLHDFVAPLR QPNRPQKKFA
PVVPIVVLSA TPISEKQHAS IAHFKHVYFL HGSPLHLNVL TTACAAKSKS VVILSSTNDD
DCDDEPDLVD ENMIDTDALT LYRFVTEFCE TSRHPDMPLP RILIVLNRPS SLRFVKDEHN
KEPADEETIE ILRAHKRQVL SRSDDPLDSI CTPIFASGKV FFPNALDALL GTCDKHGSII
DLMYLFILGE PPRGDEAGRC LDQITIPPTL WGRPYGACFE SLLLHHNILC LGLYRPQTHQ
NSYVYVNPSA DVFVTPKDIL FVLR
//
