ID A0A067D227_SAPPC Unreviewed; 447 AA.
AC A0A067D227;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
GN ORFNames=SPRG_02489 {ECO:0000313|EMBL:KDO32791.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO32791.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO32791.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO32791.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; KK583194; KDO32791.1; -; Genomic_DNA.
DR RefSeq; XP_012196453.1; XM_012341063.1.
DR AlphaFoldDB; A0A067D227; -.
DR STRING; 695850.A0A067D227; -.
DR EnsemblProtists; KDO32791; KDO32791; SPRG_02489.
DR GeneID; 24125042; -.
DR KEGG; spar:SPRG_02489; -.
DR VEuPathDB; FungiDB:SPRG_02489; -.
DR OMA; HNDLIPR; -.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF66; ETHANOLAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 34..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 50877 MW; AC42690D7EB57AC8 CRC64;
MDKTSQSPLT LDVLVLVVST CVCAYATYRL LAPSSAPPPS SRTRALPAIT TPMTSKTPPA
KPESMYLNNS KTMYDFTVGG RGEHFEFDDC KHVVKHICPR WKDAQPDDIT VKIICGGITN
RLYRLLWKDL CVLVRLYGEH TEVFIDRNVD NENFAELSRR GFAPTYFGRF TNGRVEGWVD
GTALEPHQMG ETSPFDLLSL IPKELGKMHA MEIDMDTRAC LWTKIQQFED LAAEISFDEP
VKRDALEHLQ LHQTIKQRVR WLQSVLPSHK NNDGKGLLET FRGSATAKLA YSFLHDSVFS
HNDLLSGNIL YNPAWGRVQI IDYEYGGYNY RGFDFGNHFC EHCGFDMNLN DYPSKDKQFI
FYKAYLSTAA PALLQSLTRE GHLDAFLGHL HEFGNVYALA AHMFWGLWAI VQAGNSTIDF
DFLDYARMRF EAFEVQLDLF CPTAKDV
//
