ID A0A067F3Z1_CITSI Unreviewed; 430 AA.
AC A0A067F3Z1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366041};
GN ORFNames=CISIN_1g014053mg {ECO:0000313|EMBL:KDO57931.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO57931.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO57931.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC magnesium. {ECO:0000256|RuleBase:RU366041}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU366041}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU366041}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC 1.A.35.5) family. {ECO:0000256|ARBA:ARBA00007535,
CC ECO:0000256|RuleBase:RU366041}.
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DR EMBL; KK784956; KDO57931.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067F3Z1; -.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProt.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF35; MAGNESIUM TRANSPORTER MRS2-3; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
DR Pfam; PF01544; CorA; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU366041};
KW Magnesium {ECO:0000256|RuleBase:RU366041};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366041};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU366041};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU366041}; Transport {ECO:0000256|RuleBase:RU366041}.
FT TRANSMEM 358..381
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT TRANSMEM 401..423
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT REGION 96..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 48540 MW; 2A3A8A3480FDD012 CRC64;
MRRTGLPARD LRILDPLLSY PSTVLGRERA IVINLEHIKA IITAQEVLLM NSRDPSVVPF
VEELQSRILC HYQATKSQIN GEDSNWTNLY DLEAPQSRTS SPQNFSGGFP QFEDENEERK
EDGKQSLENR DGSKVLPFEF VALEACLEAA CSCLENEAKT LEQEAHPALD KLTSKISTLN
LERVRQIKSR LVAITGRVQK VRDELEHLLD DDEDMAEMYL TEKLMQQLEN SSTSSINERD
DMDDEVLQSN MNNRTTAEIS LEATGGSTSY EADFQNTENI HDNLFTQNIH SRASHGTRTS
TTHSAISKHL DVEELEMLLE AYFVQIDGTL NKLSTLREYV DDTEDYINIM LDDKQNHLLQ
MGVMLTTATL VVSAFVVVAG IFGMNINIEL FDEHKSGMQE FLWTVGGGAT GSIFLYVVAI
AWCKHKRLLE
//
