ID A0A067NHH3_PLEOS Unreviewed; 502 AA.
AC A0A067NHH3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Aldehyde dehydrogenase domain-containing protein {ECO:0000259|Pfam:PF00171};
GN ORFNames=PLEOSDRAFT_1114338 {ECO:0000313|EMBL:KDQ23226.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ23226.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; KL198013; KDQ23226.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067NHH3; -.
DR STRING; 1137138.A0A067NHH3; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1114338; -.
DR HOGENOM; CLU_005391_0_0_1; -.
DR InParanoid; A0A067NHH3; -.
DR OrthoDB; 216092at2759; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07091; ALDH_F1-2_Ald2-like; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000027073}.
FT DOMAIN 30..494
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 269
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 502 AA; 54186 MW; 74EB940DDDB5F13D CRC64;
MPETFTYQFD TPAFKGASTI NTGLFIGGKW VDSVDGDFID IVNPATGTRI TKVVAASAKD
IDIAVDTAKQ AYKTAWGMRV PGKTRGRIIN KLADLIEKYA DEMAALESLN TGKIFNNSRR
GDINSAIEVF RYYAGWADKI HGKVIETHEH ALAYTRHEPY GVCGQIIPWN FPFSMLSWKV
APALATGNVV VLKPSEITPF TALRFADMLN EAGVPPGVVN IVTGLGPIAG QAISEHQKVD
KVAFTGSTLV GRKIMEAAAR SNLKAISLEL GGKSPNIIFD DADLEQTVKW TAFGIFSNMG
QVCAAGSRVF VQEGIYPKFI EAFTKAAQGL GTAIGDPFAK ESKHGPQVSK TQFDRVMGYI
ESGKEAGANV AIGGHKHGNN GYFIEPTIFT DCRPDMKIVQ EEIFGPVAAV IKFKTEEEVI
QMANDSIYGL ACAVFTENGS RALRVIHALE AGTGFVNCYN TVGPSVPFGG YKQSGIGRDL
GQYALDTYTQ VKSVQVNIGQ KL
//
