ID A0A067P251_PLEOS Unreviewed; 749 AA.
AC A0A067P251;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=PLEOSDRAFT_1081613 {ECO:0000313|EMBL:KDQ29941.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ29941.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|ARBA:ARBA00004987}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; KL198006; KDQ29941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067P251; -.
DR STRING; 1137138.A0A067P251; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1081613; -.
DR HOGENOM; CLU_004542_2_3_1; -.
DR InParanoid; A0A067P251; -.
DR OrthoDB; 5486783at2759; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF10; BETA-GLUCOSIDASE F-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023001};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KDQ29941.1};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023001};
KW Reference proteome {ECO:0000313|Proteomes:UP000027073};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..749
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001647185"
FT DOMAIN 671..740
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 749 AA; 80486 MW; E07F71714F2D858C CRC64;
MALSQLRLTV LLLPYFILCA SAFTTRSWQA ASQLAAQKTA AMTIDEKVGV LTGVTMAGSR
CNGDTHPVAR LGIPALCLMD GPAGVRPGTG VTGWPSGINA ASTFSRRLIR ERGAAIGDEL
RGKGIHVWFG PAQDLMRNPK GGRGWESFGP DPYLNGEGGY ETIVGIQSKG VQACAKHFTA
NNQEHNRYNG SSTVDDRSLW EMYGYPFLRS IEADVSAIMC SFNRINGTFT CSSPKLLSDT
GFLRSNGFKG YVITDWGADH GFAAENANAG LEMEQPGEYD PQPSPLVEGG GLFANGGLKD
SVLNGTVSAA RLDEMVKRVL TPFYRLGQDS GFPETNFHTQ QTGGPYNQNI VVRTPQHVAL
AKEIASASAV LLKNVRPIRR PGQWYGNGGQ NQREYGLPVT KSKIANMAVI GEDAKLMDRS
LCNSLNECTL GTMSVGWGSG ANSLEFLVAP ADAISAYVGT SATIASSLSN DAAAGAAAAA
GKDVAFVFVN AMSGEWIVDI VHDQGGDRND LELYYNGKEL IESVAAVCNN TIVIVHSVGP
VLMPWSTNPN ITAIVYAGAP GEQTGPSIVD VLYGHYNPRG RLPFSIADSE AAYGTEIVYD
KTIGPLTIDY TEGLFLDYRY MEQNNITPRF EFGFGLSYTA FSYSNLQISN QGPFKVIKFK
VRNTGSVDGT EIPQLYLGFP NGSGEPKKVL RGFSDVGLTV GSSKTVEVKL SVRDRSIWDV
VTQKWVVPSG QFKVYIGASI KDIRLTGTF
//
