ID A0A067QLP6_ZOONE Unreviewed; 3501 AA.
AC A0A067QLP6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Myosin-XV {ECO:0000313|EMBL:KDR10067.1};
DE Flags: Fragment;
GN ORFNames=L798_15304 {ECO:0000313|EMBL:KDR10067.1};
OS Zootermopsis nevadensis (Dampwood termite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Termopsidae; Zootermopsis.
OX NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR10067.1, ECO:0000313|Proteomes:UP000027135};
RN [1] {ECO:0000313|EMBL:KDR10067.1, ECO:0000313|Proteomes:UP000027135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole organism {ECO:0000313|EMBL:KDR10067.1};
RX PubMed=24845553; DOI=10.1038/ncomms4636;
RA Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA Liebig J.;
RT "Molecular traces of alternative social organization in a termite genome.";
RL Nat. Commun. 5:3636-3636(2014).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KK853186; KDR10067.1; -; Genomic_DNA.
DR STRING; 136037.A0A067QLP6; -.
DR EnsemblMetazoa; KDR10067; KDR10067; L798_15304.
DR eggNOG; KOG4229; Eukaryota.
DR InParanoid; A0A067QLP6; -.
DR OMA; TFGVHQN; -.
DR Proteomes; UP000027135; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009887; P:animal organ morphogenesis; IEA:UniProt.
DR GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13201; FERM_C_MyoXV; 1.
DR CDD; cd01387; MYSc_Myo15; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 3.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR041795; MyoXV_FERM_C.
DR InterPro; IPR036057; MYSc_Myo15.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR22692; MYOSIN VII, XV; 1.
DR PANTHER; PTHR22692:SF26; MYTH4 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00784; MyTH4; 2.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00295; B41; 1.
DR SMART; SM00015; IQ; 3.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 2.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000027135};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..665
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 844..993
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 3028..3183
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 3188..3496
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 537..559
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1250..1351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1395..1419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1592..1614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1653..1728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1797..1835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1870..1908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1938..1995
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2332..2363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2678..2699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2717..2765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2910..2962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 738..770
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2853..2880
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1251..1297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1331..1347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1653..1701
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1702..1720
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1819..1835
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1884..1908
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1968..1988
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2332..2356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2717..2731
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2743..2765
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2916..2954
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 69..76
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KDR10067.1"
SQ SEQUENCE 3501 AA; 394287 MW; 9179FA4C2B3C04AC CRC64;
LLQTYTGSIL VAVNPYKMFD IYGLDMVKKY EGQILGTLPP HLFAIGSSAY GHMSKEGSSP
ESQVVVISGE SGSGKTESTK LVMQYLAAVN KSPSNLITEQ ILEASPLLES FGNAKTVRND
NSSRFGKYLE VHFKGGVIIG AKITEYLLEK SRIVTQAPDE RNYHVFYEML QGLTSEAKEK
YGLLSPDKYF YLNQGGNCEI DGKFDGEDFQ SLLSAMQVLG FTSDEQDTIF RILASVLHLG
NVYFHRKQLK HGQEGVEIGS DAEIRWTGHL LHLNPDGIKR ALTTKITEAR NERVVTPLSI
DQALDARDAF AKALYNALFS WLVSRINQIV YKGTKRTAAI SILDIFGFED FKENSFEQLC
INYANENLQF YFNKHIFKLE QQEYAKEKIE WQTISYTDNM PVIHLIAKKP VGILHLLDDE
SNFPKATDLS FLEKCHYNHA LDELYSRPRM SSMEFAVKHY AGQVWYSVDG FLDKNRDTLR
QDVVDLLISS KIQMVSKMFQ HVRSSHEAAK TINKANGRFV TMKPRTPTVA ARFHDSLQHL
LESMSKCNPW FVRCIKPNSD KAPMKFDMPI VLEQLRYTGM LETIRIRKMG YPVRLRFSQF
VERFRYLLPQ RVGGLTTRGT PYRELCRVIL SSCCPEAETN GDYQLGTTRV FLREWLEREL
ERERARVVRA AAVILQKTVR GYLARRRYRA TRKAALTLQA HVRGWAARKR YRAVRTGVVR
VQANFRAMRQ RKRYLELKEE LKRRAEVEKL ARERAKAKAQ REEQERASRA VAGVNHLEIP
AELAFIFSKL DDWQPVHSER HLVKVVGGVA GCPDSERHRL PHDIDSHAFT KFTNIYFKSH
LWGMKREPIK TPFLAKSKDM DYQDSLALFK LILRFMNDNN LSGKKEIALG DYIVNKGIVN
EKLRDEVLCQ LCNQTWNNDN DANNERGWQL MANCLSVFPP SKTLYKYLLK YVSDHGYNGY
KAVCQRKLLQ SSRIEWQLAR NYPPCLLEWR ANRKRVNMAL QIYFADGEMV SVPVESWTGA
EELCGRAVWE RGITESLGWT LCLSTGTDNV DSSMDGLIKE INGLDYVLDL IAEMELAPAF
PACRSGFLQS GGYSRGPRHV NNKVRMYIYC MSRAELEIES DVPAPSSPRR PVVPPPEPPV
VKQPVSILVR SQSRDHTVEN ALSRKSALND RYFEDKGRSR SLDNLLESEL PAPRKLDSLG
LSQSRLNERY HSMEKVNASH SDVSMLLNAV SNKEYMTKAE ALLEEQLESV SQRGESNHRK
YSLLDSSSNH RDDMDFDYPD LASQTRSEDD KGSYIKGHPR FIKSQYAGKR AAPGSHSSRA
YIETRNSEKS DYGAKSSALS DTSEAPSLAS HVRRVRVPSQ ASDVDQFLDD LFMPVLDGNL
DELSDARSLA ASIKGGGELS KNGAEQQRTR RLSDSSSLVD DEVATLTGSS AASTLSLQRL
TTAVTLAGAI KGGGGMDSHQ SSGSLTYMGP AGGMAGAAQA MAAMPQFYST PVSADQAGFM
PIPIYNMQGM SLPTFPTPGQ QQAGSAGVDP AVAVYQQNLQ RAFLQSAMAQ NIQIQQQLLA
QNQALQQMLV QPTLTAQQQT PVSFREPENG ELWSTEKRGG SSAAMAPVST GMPLQQQIPP
PPLPPKSHFN PASPYQQQNP NFVKHETTVK AQLRLSPTRK LSPTKTAGSG NPQAAFTNVL
SELKSRRSST ESGYSNKMNS SGNAPPPPPP MPPPPEHMDP SETRPFLDPY GRAKTVRIGK
WRWPPPKTDQ DESSDSFLQF KMRQHQRKTT PQQQLNSQEF GELSEGIEWE EFEITGSPGA
ASHERSPPAN AGVSRKDSRS GNAGHHRLLD GKDKNSVRAF EVGAARPSPG SIGKLHISSE
MRTKLEMVTA NHSLRASNKP EKPGVIPSKR DDSSPPSPHR PVKKLEDNRR LMLEQQLAGR
WDSVDSVDIL TSTPLRGVSK EERSEVQQTN IVRTPPPPPV TPHFIETSPP AASRTGSFYS
QGQNTALPQP RSPPLPIQPV KTSRDSAMYQ HNNKQHSNDH DMFTNAYNSS QYHQLSQHTN
NAFRGRDMFE QSGGVARVDR DCRSSVSTHL TDRMERIEIE ESPEFLQPVD IAPPLIMERR
DHGKNLEMVK TKLFGPSSAA YFTYNRVTWR LCVRKEVFAP GETLGSPLAL HLVFCQVVQD
CLYPTNCIRV SREQRSKMRK LLDSYGVTIN NLHSSHQKVT IKKNIVDMAK DWPLYFSRIF
PVSGGHQHPA VQQLAISHSG VRLVRREKGP IEDALQVLDA FSFEEISETC VPKGSAVQLV
LTSGIRFLLY SHRANQIHAM IEKYCLDNEK VGKQLYYFVK LEVLTAVMTE ATDHNSRRKQ
NQSPDERRDQ LDRDMKSNWD QLPATLRRRK EKLSQAVLDQ FTEDEIQPDL ATDLNKQNGV
LQKVSDDSVY LASLEGIQLS ADRHSTEVLV VEENSASAES MRRSSNNSSQ IIVTPQIHRE
CSDSSLDCIE NKAEDLSVEL GNDDNLVPPN NLEAETKKEI EIHAKTEIKL QTDTSEECNK
SNIETHKSAQ TETQFKDSSV TQLELENMTQ KMEEFTATCS REITLKYNSQ DENVDDASSF
QEKDGVLVIT ENENCSNVSE NIDDNYDKNE IVLSQNKLSE TSDFKGLDNY DSERVNSENI
TTFEKLLLPD ESCLYESNKE DKNTSVFCET QKSPTNLELP ATKEFSEEAH TASTPLSEEE
QQIMALLSRA VSEDSLLIPS SPSSASAKSV TLSVDDGDHD SGTDINSPSP STSSSNMESR
STSTSKLDIY GSKWKRPFGL ETLNKKSVTM ATIMEEREGE ADTSATTTNT SDSEKLTVRE
ILRRFEELGG RVHLPTDIAH VEGDSDAEKS ATLRDIQETL RCLEEKVRHY ETKAATTQTQ
DADENSSSEK VECSYVTILD LSVLNSRKFH GAGRHQQAPS HQQSPVLQSH ASTTSTQHQH
QQRSVITSSP QPPEPSGHHD GKHSLLQFAM LHFRQSPEKF EMLKTADGSI SGSLKVIESL
KANKKNKGKR GSKDTDWTWK EQVDLVKFTS VPIEQSLLRL EPGELSELAV ECFAAVMRYM
GDLPMAPDST EVKCVYTILM HCHKHEALRD EVYCQLMKQT TNNKSMKPDS CQRGWRLFSI
VAAYFVCSDT LKPYLFKYLE TAAYDKRRAF HGTATVCLQN LRKTFKYGGR KNVPSVEEIT
AISAGRNSKR QIYRLPGGTE RVVNTKSTTV VQDVIEELCS VIGVVGGEME LEEFSLYCIV
EGDTFTMPLA REEYILDVTT ELHKNQQVFY LIFCRSVWHF PLRLDSQLYV EVVFNQIAPD
YLEGLLLIMP GEQLDQDVIY DIAKMAALLH RAADMTHVPT MKETKFLLPK PALTVRDVKP
AQWVNMVQSN WRDVEMLTTI QSKAQVLDIL SKWPLFGSSF FAVKRVSDPK ERSDHILALN
RHGVHFIDLV THETLTHYPF SEVISTRKVK SEDGTLFLDM KCGNLMQQRI TRLQTDQAHE
ISRLIRQYIT MEQRLQHRSA A
//
