ID A0A067QSH7_ZOONE Unreviewed; 619 AA.
AC A0A067QSH7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Kelch-like protein diablo {ECO:0000256|ARBA:ARBA00013699};
GN ORFNames=L798_12031 {ECO:0000313|EMBL:KDR12596.1};
OS Zootermopsis nevadensis (Dampwood termite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Termopsidae; Zootermopsis.
OX NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR12596.1, ECO:0000313|Proteomes:UP000027135};
RN [1] {ECO:0000313|EMBL:KDR12596.1, ECO:0000313|Proteomes:UP000027135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole organism {ECO:0000313|EMBL:KDR12596.1};
RX PubMed=24845553; DOI=10.1038/ncomms4636;
RA Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA Liebig J.;
RT "Molecular traces of alternative social organization in a termite genome.";
RL Nat. Commun. 5:3636-3636(2014).
CC -!- FUNCTION: Probable substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex which mediates the ubiquitination and subsequent
CC proteasomal degradation of target proteins. May have a role in synapse
CC differentiation and growth. {ECO:0000256|ARBA:ARBA00043912}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; KK853004; KDR12596.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067QSH7; -.
DR STRING; 136037.A0A067QSH7; -.
DR EnsemblMetazoa; KDR12596; KDR12596; L798_12031.
DR eggNOG; KOG4441; Eukaryota.
DR InParanoid; A0A067QSH7; -.
DR OMA; IETYDAR; -.
DR OrthoDB; 5472491at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000027135; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000027135};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 35..102
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 619 AA; 71161 MW; 95DBCDCE929B4F41 CRC64;
MELNQHSCCS QHGRWCICTE ALLALNDLRQ KTLLCDAVLR LEDGGVFPVH RVILSACSTY
FRYLFTTFDT KEQNEILLQG ISSYIMTQIL DYVYLRKIHI HCDNVCQLLV TADYLCVLSV
LELCCEFLKH KLGFENCIGI MLFARCYFCT DLENHARRFI LRHFVQVSQQ SEELLELPAE
ELQAIIGSED LNVKNEKVVW ECILRWINHD PDNRKSHFVD LFMNVRIGLL ETRFFHEKVR
NHPYVKENMA CKPMIVEMLT FLYDVQTITK KAERVLLPKI AYPRIPQDIL FAIGGYRDGI
PTDVIETYDT RADRWINMEE VDPFGPRGYH GTAVIGFNIY VLGGFNDVEY LNSCRCFNAV
TKTWSEVAPM NSCRSYFCVA VLGEVVYAIG GHNGFHRFKT AERYDYNTNQ WSLIAPMSTE
RSDASATELN GKIYVVGGFN GWNYMNSAEV YGPETNQWTL ISPMLSQRTG VACTALHGCV
YAIGGFNGIS RVCSGEKYNP ATNTWTQIPE MYEPRSNFAI EVMDDMIFAI GGFGNVDATY
CVECYDEITN TWYEATHMNI YRSALSACIV KDLPNARDYV YKHRERLLED LRQNKLAMEI
HGDLEYEALG DNINFDFDF
//
