ID A0A068QQH4_9GAMM Unreviewed; 1073 AA.
AC A0A068QQH4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN Name=ftsK {ECO:0000313|EMBL:CDG17257.1};
GN ORFNames=XDD1_1558 {ECO:0000313|EMBL:CDG17257.1};
OS Xenorhabdus doucetiae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351671 {ECO:0000313|EMBL:CDG17257.1, ECO:0000313|Proteomes:UP000032721};
RN [1] {ECO:0000313|EMBL:CDG17257.1, ECO:0000313|Proteomes:UP000032721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FRM16 / DSM 17909 {ECO:0000313|Proteomes:UP000032721};
RA Genoscope - CEA;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; FO704550; CDG17257.1; -; Genomic_DNA.
DR RefSeq; WP_045969949.1; NZ_VNHN01000001.1.
DR AlphaFoldDB; A0A068QQH4; -.
DR STRING; 351671.XDD1_1558; -.
DR KEGG; xdo:XDD1_1558; -.
DR HOGENOM; CLU_001981_0_2_6; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000032721; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 717..930
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 211..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1054..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 302..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 734..741
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1073 AA; 118958 MW; 6C564DCAAD34EEDC CRC64;
MNQEYTEDKR VKLKKISSSR RLLEAILLVI AICAVYLMVA LISFNPSDPS WSQTSWHEPV
HNWGGSVGAW LSDTLFSAFG ILAYAVPPLM LLGCWNAFRQ RDRQEYIDFF TLALRIIGAL
ALVLTSCGLA ALNIDDLNDF AAGGVIGNLF SNAILPWFNI LGATLALLGI WAVGFTLFTG
WSWLTIAEKI GAVILDSLSF VVNRGRNDAE YNEEDSEDAL VSESPVSEQK RVEHADKHEM
VNSAVTIETP DADEDDVLLT TPTVVELANT DPVLQPAPAS PVMEENGSSE TTEHPLEREH
IPQSVISTTA TSSPAFDQPE FEQPELQHQE EENRDDDVTD TMTSPETHHA NVKNAAAGVT
GSVAVVRNPQ VKQGIGPEMP RPNPVRIPTR RELYGIKVPS HRLAEHMQRK EKERQDELIA
EANEQQMDVQ QQDILRQQFL EQQRERYGAD FEAENRGTHG EGTLLHKQPT IAELTKNSVV
DEQPDDQKAQ EEALRIAFEQ QQRERYQINQ PASPEPVSAP DEKPASNHLP QASDLNQPDL
AKFVSTEPPI QQAIPVQQPQ QDSLFHPFLI RNDQPLPKPT TPMPSLDLLA APPAEEEPVD
MLALEQISRL IEARLNDYRV KADVVGFSPG PVITRFELDL APGVKASRIS NLSRDLARSL
SAVAVRIVEV IPGKPYVGLE LPNKKRQTVY LREVLDCEKF RDNPSPLTIV LGKDIAGQPV
VADLGKMPHL LVAGTTGSGK SVGVNAMILS ILYKAKPEDV RFIMIDPKML ELSVYEGIPH
LLTEVVTDMK DAANALRWCV NEMERRYKLM SALGVRNLAG YNDKIKQAEN MGRPIPDPFW
KPGDSMDATH PMLKKEPYIV VMVDEFADLM MTVGKKVEEL IARLAQKARA AGIHLVLATQ
RPSVDIITGL IKANIPTRIA FTVSSKIDSR TILDQGGAES LLGMGDMLYL APNSSIPVRV
HGAFVRDQEV HEVVNDWKAR GRPQYIDSIV KGGEDGEGSM GFDSDEELDP LFDQAVEFVV
EKRRVSISGV QRQFRIGYNR AARIVEQMEA QQIVSAPGHN GNREVLAPPP HEH
//
