ID A0A068R1Z4_9GAMM Unreviewed; 2886 AA.
AC A0A068R1Z4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Putative Phenylalanine racemase (ATP-hydrolyzing) {ECO:0000313|EMBL:CDG21267.1};
DE EC=5.1.1.11 {ECO:0000313|EMBL:CDG21267.1};
DE EC=5.1.1.12 {ECO:0000313|EMBL:CDG21267.1};
GN ORFNames=XPG1_1612 {ECO:0000313|EMBL:CDG21267.1};
OS Xenorhabdus poinarii G6.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1354304 {ECO:0000313|EMBL:CDG21267.1, ECO:0000313|Proteomes:UP000032735};
RN [1] {ECO:0000313|EMBL:CDG21267.1, ECO:0000313|Proteomes:UP000032735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G6 {ECO:0000313|EMBL:CDG21267.1,
RC ECO:0000313|Proteomes:UP000032735};
RA Genoscope - CEA;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FO704551; CDG21267.1; -; Genomic_DNA.
DR RefSeq; WP_045958489.1; NZ_FO704551.1.
DR STRING; 1354304.XPG1_1612; -.
DR KEGG; xpo:XPG1_1612; -.
DR HOGENOM; CLU_000022_11_0_6; -.
DR OrthoDB; 9757559at2; -.
DR Proteomes; UP000032735; Chromosome.
DR GO; GO:0050157; F:ornithine racemase activity; IEA:UniProtKB-EC.
DR GO; GO:0047462; F:phenylalanine racemase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 2.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:CDG21267.1};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1062..1136
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2563..2638
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2886 AA; 322942 MW; E6FF8D26A0CB1BE7 CRC64;
MLMLLKELKK NHVSVWASQD KLKLAFAGET PPTQLIDRVK EKRENLLTFL NESNIFSEED
FAHFALGENH SDVIAAPGNS GSQGEKDSNI EVIFPATSLQ QGFIYHHLTQ PQDDAYRVQL
LLDYYTHIDL AAYQHAWALA SLRFPILRTA FDWEGDILQI VTAGASIRSA NFTIKDISQL
PEEARDSAIA GFQQHDRNLP FDLHQPGLIR FTVIKQHEQW ITVLITQHHC IADGWSGPIL
LQTVHEYYNQ LIKGHVPTVV AEPAYLATLQ YHLDHQAESD AYWAACKKQF QNTNDLFALL
STHVDLARIK TVEKPAEQQL SVQREIYQQL KRTCQTQNVT LNVALQFAWH KLLHSYTGDE
QTIVGTTVSG RDVPIEGIES SVGLYINTLP LVVSWAKADS IATILHNIQH AIVALNNHSA
VSLASLQSDG ERLFHSLLVF ENYPAPVLSE NGDGIEQALT FRQAVEKVDY PLSLLAYEQD
ERLIIKLSYG EDWLTAQQAQ RLLDQLERIL HAVACHPHQA HSSIQLLSEK ERHTLLHTWN
QTDAPYPQDK TLHQLFEAQV TKTPDEVALI FGTEALTYRQ LNAQANQLAG VIRERYQQHH
HASVQAGMPI ALYFDRSLEM VISILAVLKA GGAYVPISPE YPAQRVQFIL SDTAASCVVT
QQRHLRVLTD YAQAIASAPI LIAADELTTT ADPWRENPPP ITQPTDLAYI IYTSGTTGQP
KGVMIEHKNA VHLITAQAEL FEVSKRKKAL MFAAYVFDAS VSELFTSLLH GLTLYICRET
ERNIPAVEQI IQREGIEIAT LPPAMLKLLI GADFPSLQLL VTAGESPSLD FLDYFSQHRD
VLNAYGPTEV TVCATGNRYH SGDIATNIGR AINNVRLYVL DEYGNLSPIG APGELYIGGA
GLARGYLNRP ALTAERFVPN PFATADDKIK GYTRLYRSGD LVRWRPDGTL EYLGRNDAQI
KIRGYRIEPG EIENTLTSHP QVKQAVVIDR EHQEHKILAA YLVTDGFVSE ETLIEYLSAR
LPDYMVPASV TFMGSIPLTL NGKLDRQALP DRVWGQQNNY VAPRNALETQ LCTIWQEVLD
LPQVGINDNF FRIGGDSIVS IKLVSRLRMA GFSLQVQSIF TAPTVARLAH LLTQTSSSVT
VIAEQGLLSG EFALLPIQQD FFNWDLPHSH HWNQAFMMQL PGHIPASAIE HALITLIERH
DMLRAHFINT PQGYRQCYPA EMPAWLPALR CCDISKLDEA ARHQQLTQWQ NHFDYCAGPL
WQAAHLTGYH DGSARLFFAF HHLIIDVVSW RIIAEDMRRL LQAERLPAKT SSYRQWVNAV
YQYAEHHQQE ISYWQQVMAE YHAHSVTSEP RQHHLSLSAT LTDVLLREAN GGYHTEINDL
LLSALTLALQ AVFSQAINHI TLEGHGRENI DNTLDVSETV GWFTTVYPVR LTMQDDIAKT
IIDTKEMLRA VPNKGIGYGA LRQAGYLSEN LPAISFNYLG QLSGETPQVW SLTSDDCGTV
MADHEVEDHR HHLLLNINGL IQAGQLQFSI HSCLPQTQTH VFITAFDQAL NAVITAGQQQ
AQAGGLKTPS DYAIAGLSGN LLRRLQQKYS IEALYPATSL QQGFIYHHLA QPHDDAYRTQ
LLLDYHTTLN LTAYQQAWTL ASQRFPILRT AFNWEDAILQ VVTKEASLGA ESFTIKDIGS
LPPEEQEHAI NAIQQHDRTV PFDLSQPGLI RFTLIKHHEQ RMTVLITQHH CITDGWSGPI
LLQAVHEYYN ALVQGQQPQI IAEQAYLATL QYHLDHQAES DAYWTTYKKQ FQGANDLSPL
LSTHVDLTQI KTVENPAEQE HAVQGETYQQ LKNTCRTQGI TLNVALQFAW HKLLHSYTGD
EQTLVGTTVS GRDVPVEGIE SSVGLYINTL PLQVQWNKHD SILGTLQAIQ QDIAALNSHS
AISLSSLQSD GERLFHSLLV FENYPVPVVH ENGDGIEHTL TFRRAIEKVD YPLSLLAYEQ
DDRFIIKLSY GEDWLTAQQA QRLLSQLERI LHAVACHPHQ AHSSIQLLSE GERHTLLDSW
NQTDAPYPRD KTLQQLFEAQ VEKTPDHVAL VFEGETLTYH QLNQRANQLA GIIRQRCLQQ
TPTGIQVDTP IALYLDRRLE MVISLLAVLK AGGAYVPISP TYPAERVQFI LTDTAAAYVV
TQQQHVATLT EYARSLVKPP ILIAADDPIM TADQPVENPA QINQSTDLAY IIYTSGTTGQ
PKGVMIEHNS VAHMVATQAN IFNLAKRKKA LMFAAYVFDG SVFELFSSLL HGLTLYVCSE
AERNAPAVAT LIQREGIEIA ALPPALLKLL IGTKFSSLQV LVTAGESPSL DVLTYFSQHC
HVLNAYGPTE VTVGATERQY QDGDMPTNIG RAISNVRLYV IDKYGNLSPI GAPGELYIGG
AGLARGYLNR PALTAERFIA NPFATTADTI KGYTRLYKTG DLVRWRPDGT LEYLGRNDYQ
VKIRGYRIEL GEIESALTSH PQVKQAVVIN REHQGNNVLI AYLVTDGFVS EEILIEHLSA
RLPDYMVPTR FTQIESIPLT LNGKVDRRAL PEPVWKNQRH YTAPRNALEN QLCAIWQAVL
GLERVGIEDN FFRIGGNSLT AIKLTTAMQS EIGIDIPLNV LFNCKSIALL SQWLEVDSVK
SSLLNFLTPE STATEKLFMI HAANSGSEVY EPLANALAGM YNCIGIDNYN FRTNNRIDSL
YQITQIYITL ILSETPIDKP IRLLGWSLGG QIAMEIAFQL EQLGAKNIQL FLLDTIINND
EIIELRNKLD LLHEYSQLTR RLQDMGASES YINTVLGAIP FESGIASCHL SGKLTHTNIT
LFKAGQMSPY FKDEVGVAMS QLIAKIPDNN ISQWAVKPLV INVVDDYYHE NMTEAISIIS
KAIINT
//
