ID A0A068RGW4_9FUNG Unreviewed; 519 AA.
AC A0A068RGW4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 03-MAY-2023, entry version 24.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=LCOR_00971.1 {ECO:0000313|EMBL:CDH49219.1};
OS Lichtheimia corymbifera JMRC:FSU:9682.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Lichtheimiaceae; Lichtheimia.
OX NCBI_TaxID=1263082 {ECO:0000313|EMBL:CDH49219.1, ECO:0000313|Proteomes:UP000027586};
RN [1] {ECO:0000313|EMBL:CDH49219.1, ECO:0000313|Proteomes:UP000027586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMRC:FSU:9682 {ECO:0000313|Proteomes:UP000027586};
RA Schwartze V.U., Winter S., Shelest E., Marcet-Houben M., Horn F.,
RA Wehner S., Hoffmann K., Riege K., Sammeth M., Nowrousian M., Valiante V.,
RA Linde J., Jacobsen I.D., Marz M., Brakhage A.A., Gabaldon T., Bocker S.,
RA Voigt K.;
RT "Gene expansion shapes genome architecture in the human pathogen
RT Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient
RT terrestrial Mucorales (Mucoromycotina).";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDH49219.1}.
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DR EMBL; CBTN010000003; CDH49219.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068RGW4; -.
DR VEuPathDB; FungiDB:LCOR_00971.1; -.
DR OrthoDB; 1359466at2759; -.
DR Proteomes; UP000027586; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR PANTHER; PTHR15228:SF25; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027586};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 357..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..236
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 412..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 519 AA; 59614 MW; 8E12605FF9287E14 CRC64;
MPASKVERKS SLSSWLKRAT STRSKRVFGT SLCKSLRYAK VSLGYVDETS VKHPEAGTIP
IVVAQCGSFL KAKGLFEPYV FLLPGDKRHV DTLQSIFDDP RQSHGLYLDW DSGRYSVHDA
ASILQRYLDQ LPETVIPREH SSSFCALMDY HEHEQATFAD HFRQLVQKLP IPHQHLLLYL
VDLLSLFASH ADANSMDASK LADIFTSRIL GESYGNHQHQ AQSLVQFLIG SQALFMKQLY
HVPQKETTTN MHHHPADLPL MAPRPVRPIP INLITKESIT FVPPTVKQPR LFGGSHEKHD
AMQRSCDDGS SSKPHTIATT TNYCQTTTVS STTFQRGRSL MDAKIKVLIR SWQDKPIGYL
IWTASIALIV AVLMYETYQA IWGTCCFEPY VFFGGFIFYW IMLIRGIQWH DGDDDSRRKK
NDHSNMDRRK YLRQRRRNEM SSSSQNGHHH HHKSNDPTTS DTMSIQSRFS EQWSMDGDKE
EVIIVRRKNR HSNQAISTKD SNASDRREEW KIRYYQGKK
//
