ID A0A068RLD0_9FUNG Unreviewed; 1038 AA.
AC A0A068RLD0;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=LCOR_01510.1 {ECO:0000313|EMBL:CDH49776.1};
OS Lichtheimia corymbifera JMRC:FSU:9682.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Lichtheimiaceae; Lichtheimia.
OX NCBI_TaxID=1263082 {ECO:0000313|EMBL:CDH49776.1, ECO:0000313|Proteomes:UP000027586};
RN [1] {ECO:0000313|EMBL:CDH49776.1, ECO:0000313|Proteomes:UP000027586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMRC:FSU:9682 {ECO:0000313|Proteomes:UP000027586};
RA Schwartze V.U., Winter S., Shelest E., Marcet-Houben M., Horn F.,
RA Wehner S., Hoffmann K., Riege K., Sammeth M., Nowrousian M., Valiante V.,
RA Linde J., Jacobsen I.D., Marz M., Brakhage A.A., Gabaldon T., Bocker S.,
RA Voigt K.;
RT "Gene expansion shapes genome architecture in the human pathogen
RT Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient
RT terrestrial Mucorales (Mucoromycotina).";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDH49776.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBTN010000004; CDH49776.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068RLD0; -.
DR STRING; 1263082.A0A068RLD0; -.
DR VEuPathDB; FungiDB:LCOR_01510.1; -.
DR OrthoDB; 5477883at2759; -.
DR Proteomes; UP000027586; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000027586};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..46
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1038 AA; 118152 MW; 6B080936B420D24D CRC64;
MLGAFPPRVS RLDGVPRPQP FPRGLPGVPR PPRFPRGLPG VPRPEVFPRR PVTNNSTPQQ
RPRQHYYRRI EQQTQRKYTV VPCVALTTGY MVSPTTMAAK WDTFQNVKIV INYNFRKITI
YFSTWMILDE LHMLEEPTVY KAEFDFRDLE VHSLHPEKDG KEGYAYFTLI AKHPPQYWKE
HPAPLFSNQQ SKWTRSTEIP MYDGTTTTST PSISPLQRQQ QESVTQYLPL GEWTAFRLQV
SLTSGSGKNR FNEVLELATA SRLVPHPNTR YRCDKKLFVV DAYEHMIPLP GNTTMRRHGL
LSSATIPSAI FENFDMYYTL ESYFSHRILI PATVDDTFYS LYADMTPIQA YSALRYMMAM
VDTGLDDDDD SSSSVTGGAT SSIESRHIWN PTEALRELMQ KPLFADMVKE TTPRNKRKHK
DNVKIRKVLV TPTTLVFELP QSEPANRVLR HFKKDADRFI RVQFIEEGQH RLQTSSRPHH
SSAEVYQRIS HALKYGIQIG KRHYEFLAYS SSQLREHGCW FFASDDTLNV DMIRNWMGVF
SNEHVVAKYA ARMGQCFSST YPTVQLQKNQ VLEEHLKDII QVVHSEENPE EKPKTYTFSD
GVGCISSSLA MMVATKMRLS GTAYPSAFQF RLGGAKGVLS VSPTIPGGKL ALRPSQKKFE
SPHRMLEINR VSTRSIAFLN RQIIVILSTL GVADEAFLDL LHEMLEELDC ITSDPDRCIA
MLRANSDEDG VSREMAALVQ HGFLASGDPY IAHLLHVYRL CKLKEAKKRA KIPVAKGAHV
LGVMDETNTL KEDEVFCQLS DSSHTEASRH IVTGECLVFR SPSLHPGDAR VLKAVDCPEL
KHLHNVIVFS SKGQRDVPSM LSGGDLDGDT YSIIWDERLY PSKEKRNREP MDVTPLEPKK
VDNVQISDIH DFFVEYIEND NLGLIANAHL VRADQSDDGV SDPICMKLAQ LHSHAVDFPK
TGVMETLPDE MRAGRYPDFM EKKDKPSYES QKILGQLYRS IKSGEFQHYR AQLRTKRPSM
TSVYVIPAWK STLHEPGA
//
