ID A0A068Y1X7_ECHMU Unreviewed; 606 AA.
AC A0A068Y1X7; A0A068Y135;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Heat shock protein {ECO:0000313|EMBL:CDS36121.2};
GN ORFNames=EmuJ_000298000 {ECO:0000313|EMBL:CDS36121.2};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CDS36121.2};
RN [1] {ECO:0000313|EMBL:CDS36121.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CDS36121.2}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN902850; CDS36121.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A068Y1X7; -.
DR STRING; 6211.A0A068Y1X7; -.
DR eggNOG; KOG0101; Eukaryota.
DR OMA; VIKHEHR; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375:SF395; HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Stress response {ECO:0000313|EMBL:CDS36121.2}.
FT REGION 586..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 68007 MW; 6E38833C833C29C5 CRC64;
MSARPAIGID LGTTFSCVGV FQSGRVEIIA NDQGNRITPS CVAFTDEERL IGESAINQAA
MNVANTVLDV KRLIGRRFDD EVVQSDMKHW PFKVINSEGK PKIEVQHCGK TKQFVAEQIS
AMVLSKMKET AEAYLGEEVT DAVVTVPAYF NDNQRNATID AAKIAGLNVL RLVNEPTAAA
IAYGMDRTSD RQRNVLIFDW GGGTFDVSIL SIKNREFEVK AVGGDTHLGG EDITSRLVDH
FVEVIKHEHR GKDLTTNKRA IHRLRKACET AKRMLSAAAS TKIAVESLFD EVDFCKTLAR
AEFEQLCMDL FIQTMDKVET TLSDAKLRKA DIHEILLVGG STRIPKVQSM LQDFFNGRDL
QRSINPDEAV AYGAAVLAAK RSGNMSKLME NLMLYEVTPL SLGWKDCYGA MVTVIKRNTR
IPTKQTCSAQ TAIDNQTRSN ISIFEGERAM AKDNNFLGEF LVQGYPARPR GEIKFVYTFE
IDENGILHVS AVEKSTGKQN SITITKYKGH LSEEEAKLML AEAEKFKQED EKERSRVAAM
NALLDCIYST KRKLEKVEVK QKMSEKNRKM LLAKCEEMIK WADREKQATK EDYERKRKQF
ESECSL
//
