ID A0A068Y608_ECHMU Unreviewed; 738 AA.
AC A0A068Y608;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=RNA binding protein Nova 1 {ECO:0000313|EMBL:CDS37606.1};
GN ORFNames=EmuJ_000486900 {ECO:0000313|EMBL:CDS37606.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CDS37606.1};
RN [1] {ECO:0000313|EMBL:CDS37606.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CDS37606.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN902843; CDS37606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068Y608; -.
DR STRING; 6211.A0A068Y608; -.
DR eggNOG; KOG2191; Eukaryota.
DR OMA; NYANIQT; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22435; KH-I_NOVA_rpt1; 1.
DR CDD; cd22436; KH-I_NOVA_rpt2; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 3.
DR InterPro; IPR047275; KH-I_NOVA_rpt1.
DR InterPro; IPR047276; KH-I_NOVA_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 3.
DR SMART; SM00322; KH; 3.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 3.
DR PROSITE; PS50084; KH_TYPE_1; 3.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 37..110
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 130..202
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 588..661
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 716..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 75848 MW; 6ACBEA17B6D79AF0 CRC64;
MTGSNSGSDD SNESRKRHSD DHFESGCSSK RPNCGASAVH LKVLIPSIAA GAVIGKDGEA
IERIQKESGA KVKMSKRNDF YPGTLERVCL IVGTLEAVTS THTFVMERIY EKPDTTIQST
DSRVVLERHK QTKVKILVPN STAGMIIGKN GTYIQEIKER SEAYVQISQK SREFSLPERC
VIVAGELHQM RAAMDLILAV IASDPQSSSC PNLSYADVRG PVSSVYPTGS PYAFPFISAS
TGNLLLRPDA SSLATAATAA ANPYLVGPLT APLNPMDAAI LLQLVNSGDH ISALQQQQQQ
QQQHNAALNA VLHMSGGSGG SGGNGLASAS GAVITANHPQ VHAYPHQPHH QQQQQHQASS
ASPLATAVAN SLGSFCSNPT FLPAAAMFDS IMPSTAAAVA AAAGPQARMT SQYLGGRGAG
AFVSASAYPS VATAATAQLC PFVPLQTTAF ASPSPPSSAT PDAPALHAAA ALAAVASANS
RTTSASTSAA TAASSAEALS IFDTGQRSGG GGSGTETEVA AAVVPPTGLW EESKSEAGQQ
PPTYLTASAA ALMGLYASAT AMANSNAIVT PTAGAQLLRS SVGGTSGLLY TREILVPESL
IGRISGPQGR LLLDLQTQTN TLIQVSPKCV FVSGLQSRVV SISGDQMNAN YAAAVIENTI
TIEQLNQHAS VLHAPLRRPY EESGAGHINQ TPGRSNGVVA SDIIGGGGGD YGPIEGVASA
GTSCPTQPSQ PLPKQPAF
//
