ID   A0A068Y683_ECHMU        Unreviewed;       483 AA.
AC   A0A068Y683;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=GLE1 RNA export mediator {ECO:0000256|ARBA:ARBA00030897};
GN   ORFNames=EmuJ_000755400 {ECO:0000313|EMBL:CDS39994.1};
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211 {ECO:0000313|EMBL:CDS39994.1};
RN   [1] {ECO:0000313|EMBL:CDS39994.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23485966; DOI=10.1038/nature12031;
RA   Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA   Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA   Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA   De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA   Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA   Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA   Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA   Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA   Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA   Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA   Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA   Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA   Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT   "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL   Nature 496:57-63(2013).
RN   [2] {ECO:0000313|EMBL:CDS39994.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the export of mRNAs containing poly(A) tails
CC       from the nucleus into the cytoplasm. May be involved in the terminal
CC       step of the mRNA transport through the nuclear pore complex (NPC).
CC       {ECO:0000256|ARBA:ARBA00024680}.
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DR   EMBL; LN902841; CDS39994.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A068Y683; -.
DR   STRING; 6211.A0A068Y683; -.
DR   eggNOG; KOG2412; Eukaryota.
DR   OMA; FAWHCLL; -.
DR   GO; GO:0005643; C:nuclear pore; IEA:InterPro.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.40.510; GLE1-like; 1.
DR   InterPro; IPR012476; GLE1.
DR   InterPro; IPR038506; GLE1-like_sf.
DR   Pfam; PF07817; GLE1; 1.
PE   4: Predicted;
FT   REGION          26..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   483 AA;  53580 MW;  579A1A693FA091AF CRC64;
     MSSSKAYFRH IGRLLKRTSL EMRRVISQPM PDPPDNIDSS HPLKPPTDSD DFLSDWWIDP
     PQTEFSLSDE LLKGMESIVT CRQCTFAILS RLLPEDPRQC QKYQILNRIQ EVETRAVVFL
     TLPPTNTGGW EDVEMVDRVN SIFTRFLEDA EVCLADANDL LKGKTVQKAP KAAQSTPPLP
     PKSDLPKDLL ISGFCQNDAL AINNTTNNSL FHLLSNPDLR VATSLVKMII GSACSQITGS
     DPEHCLNRLN YLLAFFEGAP VRPPGAAAEV FRLPQDMGMA FAWHCLLNAA LAQAERQFAF
     SLHSVLPFAA VLATLLARYP EYIPNFLARM ASACPVLTSY VDDSATTFAS LDVELDEGVL
     QCWRGISRLF AAVLLARPPP GFTQRPEHLN PKLLWITIAG IARHEGKLDI TSEVLHGLIE
     VGGYVLLQLY QRQARRLFKS LIDAVGDSQS VSQLALITCL EQLLDPTTAT ENGHGVLLDD
     FWN
//