ID A0A068YCY4_ECHMU Unreviewed; 634 AA.
AC A0A068YCY4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Glycerol kinase 5 {ECO:0000313|EMBL:CDS40192.1};
GN ORFNames=EmuJ_000775900 {ECO:0000313|EMBL:CDS40192.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CDS40192.1};
RN [1] {ECO:0000313|EMBL:CDS40192.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CDS40192.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156}.
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DR EMBL; LN902841; CDS40192.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068YCY4; -.
DR STRING; 6211.A0A068YCY4; -.
DR eggNOG; KOG2517; Eukaryota.
DR OMA; CTFLTWN; -.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR PANTHER; PTHR10196:SF68; GLYCEROL KINASE 5-RELATED; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:CDS40192.1};
KW Transferase {ECO:0000313|EMBL:CDS40192.1}.
FT DOMAIN 74..302
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 473..551
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 634 AA; 69458 MW; BE8D6448A09C95D4 CRC64;
MLFQRLTIGF INLVARCRVS KSTRVFVGKE NIMPSERRPL RNLIAAVDFG STHACARIYN
DKCLAEAILP SNTSDPEACW SVLCNLLQSV ITRSGIRTSD VYCLGLSVQR NTFLIWNRET
SVPVTRLCTW QEINASAYAS NRNNSQFIKA LNRSGKMLYK VVPNAKFKMI SHYKLTCIFA
VTRLAHMFDE DPMLYEKCRD GEFVYGCLET WLLWRLTGGR AWCTDVSCTS ATGAFDPSIP
GLSPIILNFL KISPKSFPAI CPTSTFFGEI HCGPLGDLGG AAKRRRVRVT AIIGDSQAAM
LGEGCLSVGD AKLTLGTGAF LNVNIGSRVI PPNTGFYPVV GWAQSARTDS SLSCEVVPDT
ELKNVTYLIE GFNSDAGSSL IKLKEAGYFQ SYTELEQILG TTSGSFDMAI ETSPFFVPSS
LGLRKVSRKR RTRSCEGEKA LTFVNTNTTL TDGGIFVGLP GPLYQRNLPT STRHAVLFAL
MDSIVMSARL LFVKGVNKEL ASDISVLRLN GNLTQSDWLM QRLADTLDLP VERSAISETC
CLGAAIAAGV GAGIWDTYAE AVQCVHEQNT RLASSKAPKA LKTRFIPNPA SAACMESRYF
HWTSVCAHTL AAHDSEFTKR KSSVALNSLL KFTK
//
