ID   A0A069JW51_9ACTN        Unreviewed;       401 AA.
AC   A0A069JW51;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Cysteine desulfurase {ECO:0000313|EMBL:KDQ65812.1};
GN   ORFNames=DT87_00765 {ECO:0000313|EMBL:KDQ65812.1};
OS   Streptomyces sp. NTK 937.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1487711 {ECO:0000313|EMBL:KDQ65812.1, ECO:0000313|Proteomes:UP000027475};
RN   [1] {ECO:0000313|EMBL:KDQ65812.1, ECO:0000313|Proteomes:UP000027475}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NTK 937 {ECO:0000313|EMBL:KDQ65812.1,
RC   ECO:0000313|Proteomes:UP000027475};
RA   Olano C., Cano-Prieto C., Losada A., Mendez C., Salas J.A.;
RT   "Draft genome sequence of marine actinomycete Streptomyces sp. NTK 937,
RT   producer of the benzoxazol antibiotic caboxamycin.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU004504};
CC   -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|RuleBase:RU004075}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KDQ65812.1}.
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DR   EMBL; JJOB01000001; KDQ65812.1; -; Genomic_DNA.
DR   RefSeq; WP_037875302.1; NZ_JJOB01000001.1.
DR   AlphaFoldDB; A0A069JW51; -.
DR   OrthoDB; 9804366at2; -.
DR   Proteomes; UP000027475; Unassembled WGS sequence.
DR   GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 2.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000192; Aminotrans_V_dom.
DR   InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR43586; CYSTEINE DESULFURASE; 1.
DR   PANTHER; PTHR43586:SF8; CYSTEINE DESULFURASE-RELATED; 1.
DR   Pfam; PF00266; Aminotran_5; 2.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE   3: Inferred from homology;
FT   DOMAIN          35..256
FT                   /note="Aminotransferase class V"
FT                   /evidence="ECO:0000259|Pfam:PF00266"
FT   DOMAIN          268..393
FT                   /note="Aminotransferase class V"
FT                   /evidence="ECO:0000259|Pfam:PF00266"
SQ   SEQUENCE   401 AA;  43914 MW;  7CEB3A3EC9827E92 CRC64;
     MRDDSVPLGE EDLSDWHNAL RAQFPIITGH PELAYLDSAA TAQKPQAVLD VVQDYLTTSN
     ANAGRGTYPW ANRTTGLIEE TRERVRTFLD DPDPAGSTVH FVSGTTEGLR TVALDWLTRE
     LADGDEIVVP FADHEANVSP WLEAVESLAR EGTRVTVREM PYQSSSGDYD TEKLRELVSP
     RTRFVAVTHV HHVYGGDMNV HRVRRAVGPD VVICLDAAQS VGHLPVSMRA LDVDFAVFSG
     HKALALPGSG AVWARGVRGA PLTPRGWSGT PNTVGIAGLG AALDWLERAG PERIERWTVD
     LAARLTEGLS RLEAFDVLGC QLSLARDSSV QRRHGIVTFR HRDIDSVDLG FILFSHGFMV
     RTDGLCQGRA GEKRTSVRVS LHAYNSRQEV TRLLDVLTGL A
//