ID A0A069K192_9ACTN Unreviewed; 757 AA.
AC A0A069K192;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Alpha-glucosidase {ECO:0000313|EMBL:KDQ70726.1};
GN ORFNames=DT87_27050 {ECO:0000313|EMBL:KDQ70726.1};
OS Streptomyces sp. NTK 937.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1487711 {ECO:0000313|EMBL:KDQ70726.1, ECO:0000313|Proteomes:UP000027475};
RN [1] {ECO:0000313|EMBL:KDQ70726.1, ECO:0000313|Proteomes:UP000027475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTK 937 {ECO:0000313|EMBL:KDQ70726.1,
RC ECO:0000313|Proteomes:UP000027475};
RA Olano C., Cano-Prieto C., Losada A., Mendez C., Salas J.A.;
RT "Draft genome sequence of marine actinomycete Streptomyces sp. NTK 937,
RT producer of the benzoxazol antibiotic caboxamycin.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDQ70726.1}.
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DR EMBL; JJOB01000001; KDQ70726.1; -; Genomic_DNA.
DR RefSeq; WP_037880988.1; NZ_JJOB01000001.1.
DR AlphaFoldDB; A0A069K192; -.
DR OrthoDB; 176168at2; -.
DR Proteomes; UP000027475; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd14752; GH31_N; 1.
DR CDD; cd06593; GH31_xylosidase_YicI; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR PANTHER; PTHR43053:SF4; RE74917P; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR SUPFAM; SSF117125; Putative glucosidase YicI, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185}.
FT DOMAIN 55..223
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 265..578
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 588..673
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
FT REGION 78..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 83342 MW; CA972677AC1CD70C CRC64;
MKFTDGFWLM REGVRASYAT EIRDLRVEES RFTAYAAVKR VAARGDTLNT PLITVECFSP
AEGVIGVRAT HHAGKARRGP DFTLFPDSPD QGATPAATRR DGPVTELTSG PLTVRADGDG
PWGLTFLDQD GRRLTAAGPK GTAFATTPDG AHHMITQLAL DVGENIYGLG ERFTPYVKNG
QTVDIWQADG GTSSEQAYKN VPFYLSSRGY GVFVNHPGRV SFEVGSEAVG QVQFSVEDQS
LEYFVVAGPT PKDVLARYTA LTGRPALPPA WSFGLWLTTS FCTSYDEATV TSFVDGMAER
GIPLSVFHFD CFWMREYQWS DFLWDPEVFP DPEGMLARLK ERGLRVSMWI NPYIAQKSAL
FAEGAERGYL VRRANGDVWQ WDLWQPGMAL VDFTNPEAAA WYEDKLRLLL DQGVDCFKTD
FGERVPTDVV WHDGSDPERM HNYYAQLYNK AVFDLLERER GAGEAVLFAR SATAGGQQYP
VHWGGDCFAS FTAMAESLRG GLSLSLSGFG FWSHDIGGFE GTPDPAVFKR WLAFGLLSSH
SRLHGNVSYR VPWEFGEEAV DVARRFTLLK HRLMPYLYGV AAEAHRTGVP MMRPMLVEFP
GDPATRTLDR QYMLGPDLLV APVFTENGEV EYYVPEGTWT SLLTGESVTG PAWRHETHGF
DSLPVLVRDG AVLPWGADER RPDGDWLDGL TLRVFGPSAA GRTVTVPDLT GATAATFHVV
RDAAGARVTA EGTTCPYRVC VEETGATGEG AGRVTVP
//
