ID A0A072PA81_9EURO Unreviewed; 676 AA.
AC A0A072PA81;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 13-SEP-2023, entry version 28.
DE RecName: Full=Nucleoporin NDC1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O9_07754 {ECO:0000313|EMBL:KEF56173.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF56173.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF56173.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF56173.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Nucleus membrane
CC {ECO:0000256|ARBA:ARBA00004232}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004232}. Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
CC -!- SIMILARITY: Belongs to the NDC1 family.
CC {ECO:0000256|ARBA:ARBA00005760}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF56173.1}.
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DR EMBL; AMGV01000006; KEF56173.1; -; Genomic_DNA.
DR RefSeq; XP_013258763.1; XM_013403309.1.
DR AlphaFoldDB; A0A072PA81; -.
DR STRING; 1182545.A0A072PA81; -.
DR GeneID; 25282667; -.
DR VEuPathDB; FungiDB:A1O9_07754; -.
DR HOGENOM; CLU_029386_1_0_1; -.
DR OrthoDB; 1929521at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR019049; Nucleoporin_prot_Ndc1/Nup.
DR PANTHER; PTHR13269:SF6; NUCLEOPORIN NDC1; 1.
DR PANTHER; PTHR13269; UNCHARACTERIZED; 1.
DR Pfam; PF09531; Ndc1_Nup; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 60..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 605..676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 676 AA; 75421 MW; 52603D92E107641D CRC64;
MSTPTPVIPA PRGYRRYLWS AFHRRLAHTV LRSLTLGVNN VVWIGSQKKY FWSWFPIGPA
FLKALVFSFS SLSIFCLQVG TLDIGLRTSS PPLATLSRNL LSLVALKTFF WYSISAFWFS
EAYIWSSPDL SWVTKGSHTT SDRLNERPIF FRAYALMLAQ AAAITHLYYG YSSLRIPISK
VPSASAPTDV ASQNTHPLES RWSQVRQAFG PAILRSARDA AIWIGLGPFL YTLLFRKILW
GCHLAFAKLW FKISRADAYP SGYPPLGIPY LTQSYLAGVF LLFTWAISKS LFLIYFTQEP
TKMGLPLSAS SKDPNGTLLL GLKAKSIVKT FAFWELTIIA QKHKDRRQTI FEDIERPTGP
MWPQMLQSGL KVLQDIELRI NGPPPKPAVA GQQQHIKTMP RIVPQLPDQS VTPPKPKPTI
RQLLVEETIG QVVSDKNPWR PPVDQTTKAV ESVFLDYFSP PFKRFITQTL GSLPSSVTSL
FITSNSAKIN ATVLGSPTGN EALIVDVIES ITKMLLASLS EDTYGKATPT VSETVRTFTK
TLTSIESFVE ANKAGTKGCI EEVEIIVERL RAGLRELLAA FQIYLLDVGL GIADLNQAKK
AVAGPQTTDI IGQPHQGKTS PDNGDQRDAF SGRQGSQRTA EYIRDQPRQQ TNNVRKRPPG
SINGRLFPRR EMEEVR
//
