ID A0A072PH21_9EURO Unreviewed; 493 AA.
AC A0A072PH21;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Cytochrome P450 oxidoreductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O9_04005 {ECO:0000313|EMBL:KEF59161.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF59161.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF59161.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF59161.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF59161.1}.
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DR EMBL; AMGV01000003; KEF59161.1; -; Genomic_DNA.
DR RefSeq; XP_013261751.1; XM_013406297.1.
DR AlphaFoldDB; A0A072PH21; -.
DR STRING; 1182545.A0A072PH21; -.
DR GeneID; 25278938; -.
DR VEuPathDB; FungiDB:A1O9_04005; -.
DR HOGENOM; CLU_001570_14_0_1; -.
DR OrthoDB; 2071324at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11059; CYP_fungal; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR PANTHER; PTHR24305:SF96; CYTOCHROME P450 MONOOXYGENASE STCB-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920}.
SQ SEQUENCE 493 AA; 55480 MW; 29B82524EF9578FD CRC64;
MTSLTTVAIV WFGLTVSEQI VYNLFFSPLS KIPGPFIAKI TTKWLTFIDL AGHRTTVLHE
LHQRYGTAVR IAPNEISFSD CGSIKDIYGQ QTAFMKAPIY DTMSVPPFGI FSMRNRADHS
QRRRLLSHAF AQSSLYESEP LIEDNVRALI SRLDNELEMP VDVMSLFRLL AFDIVGDLFL
GQAFGGLASK DPPQFLHDMD LHFMCCAIEA NSPLLYAVLS RLPIPQLRHF FQSRERLGVY
GQKALSSYLS KHGRESDRKD LLKKVVSLKT ETGTPPLTDK ETYTEIGNLV AAGTDTTSMT
LTYMFWQLGK NPDWQEQLRK ELRTHLSNEH GVIPSYNNVN QLPILNATIH EALRLHPAAP
ASLPRETPKG GKMLNGYFIP EKTIVSMQCY TTHRDPDTFP NPNNFDPTRW LDQESEDMKD
LFMPFSKGPR ACLGKNLAMM ELKLTTAVLV KDYKVKLAAS CTDDSMAMTD HFLIIPKGGK
CELLFSAAKC KAS
//
