ID A0A072PQK5_9EURO Unreviewed; 1335 AA.
AC A0A072PQK5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=CAP-Gly domain-containing protein {ECO:0000259|PROSITE:PS50245};
GN ORFNames=A1O9_05680 {ECO:0000313|EMBL:KEF57760.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF57760.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF57760.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF57760.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00011010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF57760.1}.
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DR EMBL; AMGV01000004; KEF57760.1; -; Genomic_DNA.
DR RefSeq; XP_013260350.1; XM_013404896.1.
DR STRING; 1182545.A0A072PQK5; -.
DR GeneID; 25280603; -.
DR VEuPathDB; FungiDB:A1O9_05680; -.
DR HOGENOM; CLU_002523_1_1_1; -.
DR OrthoDB; 9423at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR022157; Dynactin.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12455; Dynactin; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920}.
FT DOMAIN 26..68
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 75..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 307..442
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 471..567
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 603..637
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1032..1125
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1150..1177
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 76..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 149967 MW; A41F5B8D6FEF9252 CRC64;
MPDLNVKIGQ TIETQDKKQG IVRYIGPLHI AAGEWLGLEL PENSGKNDGS VKGERYFQCT
PGYGIFVRKE SAARIVKQQP QASKPPGQPM SNGATAKSRS SSVVPADVAR KRQSMMSAGS
GSTVGSRLSL RSPTKSPTKP TQSAASSSTS TPRTGTPATT ARTSDSSTKS RSSITGRPLM
GPPASTSRTT TTTATNRQSL GVAPKPTITR PTSMPPRQST AGTRLSMSSK TLARPEKNDQ
RPAVAIDQHS PPIEEEEAVT QEIHHAEDDP HQGSPVGHDT TSPVLSPRPH SIAVPRNAPP
STIHEDRSRQ AQVIKQLETK IRALQKQKQE DQSQLENIQD LQNQTARYEG IIQTLQKKLK
TNQQEIIELK AKYEDAEDRA SKLAEPSAEH ESELELATLD KEMAEERAMM FETELEALKS
KHEELELEVD ILREENRELT SVMTPEERAG SGWLQMERET ERLRQALVML RDMSHQNEND
LKSEIKELQE TLDELEQVAS KYEDTATKLG RAEETNTHLR EQLDALETND EILEVMGAER
DQNRNSIENL KRQIQDLEEH IQVTDELEAF HVEEEKRLHH QLDESEALLN ERLRRTTEQD
KTIEDLEYTL NKFRDVVQGL QNDIDELRRS RDISELEAHE MSSKSRAMMD LNLKLQNSAA
KSQLKAIDLE LGKMRAEQAS LHLEIVQLFI PDTFEMDKQP IVALLCFKRI KAKALLSKNI
LGERIRERPE LVQDGVSTVF AVMEKMNYIA NVCERFVQHM SSCSAENFMK FGGAPFELEP
VEQAITSWVE ALRRDELAPD GAEHLHRMAG ILVDMAEKLI LETQESKSTE LLASMSMIEC
YTDTIGSQAQ LLSKAVQTRL GPSENEDDPS IVFEKKMDQL GVKARTMKYV SSKIIQSLSD
LRTRSMSPGE ASWGLFSEAE QLSEKLARLV RGISQAVIED LNKPDHDEQL SYSTVVELMA
TAAVPMLQRD ESESGTSEDI FSILAKHLQV LQTRVDDLYS RSSDVNNAVE FEKLAAPWIA
RAKEVKSQKI LSQALQEEMA RMRSRIQEQT IRVSERDKQI EEQQVKIELL ESRAKETKAK
DDGVKAMKVE IENLQSEKQH ANESLQKLEA EYNTLLKSQQ DSRIELEAIK QSKLSDGQSL
ALGVADESLS LRLKAEADLL KVELASLEAA VRFVKAENQR LRLPVTEAGV TAISNSWLDP
DKLKPAKDTS QVQEMRSDSK QIFTELIHMA KQAKPVKLKA KSIYATEAKG HMSWWRPESD
TTLYQLLRQK EDLERWNQAK TDVVKRARLM SRSSREDDFA VPRLGIGLPL AKLPVLEDID
METESAGNGV RIVQN
//
