ID A0A072UBK3_MEDTR Unreviewed; 700 AA.
AC A0A072UBK3;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Cyclic nucleotide-gated cation channel protein {ECO:0000313|EMBL:KEH26841.1};
DE SubName: Full=Putative potassium channel, voltage-dependent, ELK {ECO:0000313|EMBL:RHN52481.1};
GN Name=25497340 {ECO:0000313|EnsemblPlants:KEH26841};
GN OrderedLocusNames=MTR_6g477760 {ECO:0000313|EMBL:KEH26841.1};
GN ORFNames=MtrunA17_Chr6g0481021 {ECO:0000313|EMBL:RHN52481.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH26841.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:KEH26841.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:KEH26841.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH26841,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:KEH26841.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:KEH26841.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH26841,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:KEH26841}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH26841};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [4] {ECO:0000313|EMBL:RHN52481.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:RHN52481.1};
RA Pecrix Y., Gamas P., Carrere S.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the cyclic nucleotide-gated cation channel (TC
CC 1.A.1.5) family. {ECO:0000256|ARBA:ARBA00010486}.
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DR EMBL; CM001222; KEH26841.1; -; Genomic_DNA.
DR EMBL; PSQE01000006; RHN52481.1; -; Genomic_DNA.
DR RefSeq; XP_013452813.1; XM_013597359.1.
DR AlphaFoldDB; A0A072UBK3; -.
DR STRING; 3880.A0A072UBK3; -.
DR EnsemblPlants; KEH26841; KEH26841; MTR_6g477760.
DR GeneID; 25497340; -.
DR Gramene; KEH26841; KEH26841; MTR_6g477760.
DR KEGG; mtr:25497340; -.
DR HOGENOM; CLU_013069_2_0_1; -.
DR OrthoDB; 3076617at2759; -.
DR Proteomes; UP000002051; Chromosome 6.
DR Proteomes; UP000265566; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45651; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED-RELATED; 1.
DR PANTHER; PTHR45651:SF11; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 20, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000313|EMBL:RHN52481.1};
KW Ion transport {ECO:0000313|EMBL:RHN52481.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:RHN52481.1}.
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 532..600
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 700 AA; 79924 MW; E9AE91A16D47B43D CRC64;
MESQKTQTSL KNGHDGALCS VVVIENKVDN FKTEKVSPFN VKGEKHWNNN HDGENEHLEK
SGLLGMCDDP YCTTCPTYFK ASQHTNPKYS NEFNPKFQNA LYGDAKGFGR DFFSFCSSCV
PGVINPHTKL VQQWNKFLAI FCMLAIFVDP LFLFLIYVQK DFNCIAIDWR MTETLVLLRS
MNDFVYFLNI LLQFRLAYVS PESRVVGAGD LVDDPKKIAV RYLQSYFLLD LFVVLPLPQI
MILTVLPRHL GLSGANYAKN LLRAVILVQY IPRLFRILSL LNGRSPTGFI FESARANFII
NLLMFMLASH VVGSSWYLFG LQRVNQCLRD ACNKSNIKGC IDIIDCGHGR NGTYQLSDQT
SVMWNNNSDA IACLNPSPNG FRYGIYVTAV PLTFETNVVN KYVYSHFWGL QQISTLAGGL
TPSYFVWEVL FTIAIIGLGL LLFALLIGNI QNFLQGLGRR RLEMLLRSRD VEQWMRHRRL
PEDLKRRVQQ AERYNWAATR GVNEETLLEN FPEDLQIDIR RHLFNFIKKI RIFSLMDEPI
LDAICERLRQ KTYINGSKIM SKGGVVGKMV FVVRGKLESI GENGIGVSLS EGDACGEELL
TWYLEQSSVS KDGKKVRLPG QRLISNRTVK CLTNVEAFSL KAADLEEVTT IFTRSFRSFL
VQGPLRYESP YWRSLAATRI QVAWRYCKKR QKLSNPTLKL
//
