ID A0A073AWL4_9PSEU Unreviewed; 366 AA.
AC A0A073AWL4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:KEI44143.1};
GN ORFNames=GU90_11765 {ECO:0000313|EMBL:KEI44143.1};
OS Saccharopolyspora rectivirgula.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=28042 {ECO:0000313|EMBL:KEI44143.1, ECO:0000313|Proteomes:UP000031419};
RN [1] {ECO:0000313|EMBL:KEI44143.1, ECO:0000313|Proteomes:UP000031419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43113 {ECO:0000313|EMBL:KEI44143.1,
RC ECO:0000313|Proteomes:UP000031419};
RA Barrera C., Millon L., Rognon B., Zaugg C., Monod M.;
RT "Saccharopolyspora rectivirgula DSM-43113 Genome sequencing.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEI44143.1}.
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DR EMBL; JNVU01000029; KEI44143.1; -; Genomic_DNA.
DR RefSeq; WP_029720059.1; NZ_JNVU01000029.1.
DR AlphaFoldDB; A0A073AWL4; -.
DR STRING; 28042.GU90_11765; -.
DR eggNOG; COG1062; Bacteria.
DR OrthoDB; 3265141at2; -.
DR Proteomes; UP000031419; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08263; Zn_ADH10; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43350:SF2; PKS_ER DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000031419};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 8..363
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 366 AA; 38303 MW; F8C022812E195346 CRC64;
MHAAVHTAPN RPLQIEELAD PEPGVGEVAI DVHSCGACHS DLHVMKGELA FPTPAVLGHE
VAGVISEVGP GVTGLSVGDP VVTSFIMPCG QCEQCARGNE EICRQFFAFN RAKGRLYDDR
TRLHRPDGEP VWMYSMGGLA ERCVTPATSV FRVPDGVALA DVASVGCSTM TAYGALRHAA
DVKVGDSVAV VATGGVGSAL VQLASVFGAS TIIAVDISDD KLTAASKLGA THTVNSAQVD
AAEAIREITG GRGVDVAFEA LGSTATFGIA RDCVVEGGQV VVVGIAPKGT TGEFDLATIA
RRKLQIKGSY GAKPRRDMPI LLDLVARGQL RPKDAITRRY PFSQVQEAFT ALDRGETIGR
SVIDIR
//
