ID A0A074VV13_9PEZI Unreviewed; 116 AA.
AC A0A074VV13;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=Transcription initiation factor IIA subunit 2 {ECO:0000256|ARBA:ARBA00019928, ECO:0000256|PIRNR:PIRNR009415};
GN ORFNames=M437DRAFT_64854 {ECO:0000313|EMBL:KEQ64308.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ64308.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ64308.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ64308.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- FUNCTION: TFIIA is a component of the transcription machinery of RNA
CC polymerase II and plays an important role in transcriptional
CC activation. TFIIA in a complex with TBP mediates transcriptional
CC activity. {ECO:0000256|ARBA:ARBA00024733}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR009415}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 2 family.
CC {ECO:0000256|ARBA:ARBA00007675, ECO:0000256|PIRNR:PIRNR009415}.
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DR EMBL; KL584829; KEQ64308.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074VV13; -.
DR STRING; 1043003.A0A074VV13; -.
DR HOGENOM; CLU_112964_3_1_1; -.
DR OrthoDB; 5052738at2759; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd10014; TFIIA_gamma_C; 1.
DR CDD; cd10145; TFIIA_gamma_N; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR Gene3D; 1.10.287.190; Transcription factor IIA gamma subunit, alpha-helical domain; 1.
DR InterPro; IPR009083; TFIIA_a-hlx.
DR InterPro; IPR009088; TFIIA_b-brl.
DR InterPro; IPR003194; TFIIA_gsu.
DR InterPro; IPR015871; TFIIA_gsu_C.
DR InterPro; IPR015872; TFIIA_gsu_N.
DR PANTHER; PTHR10966; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR PANTHER; PTHR10966:SF0; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR Pfam; PF02751; TFIIA_gamma_C; 1.
DR Pfam; PF02268; TFIIA_gamma_N; 1.
DR PIRSF; PIRSF009415; Hum_TFIIA_gamma; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:KEQ64308.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR009415};
KW Protein biosynthesis {ECO:0000313|EMBL:KEQ64308.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR009415};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR009415}.
FT DOMAIN 7..53
FT /note="Transcription initiation factor IIA gamma subunit N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02268"
FT DOMAIN 64..103
FT /note="Transcription initiation factor IIA gamma subunit C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02751"
SQ SEQUENCE 116 AA; 13190 MW; 3835DFD8EFF17B6C CRC64;
MAEQSMYHEM YRNASIGGTL ADTLDDLISS RRIEPQLAIK IMTNFDKAIA QVLGEKVKAR
MSFKGHLDTY RFCDDVWTFI LKDVKVKLDN SQQIEVEKVR IVSLLNANSA HNSGKK
//
