ID A0A074W8A2_9PEZI Unreviewed; 829 AA.
AC A0A074W8A2;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 22.
DE SubName: Full=Cora-domain-containing protein {ECO:0000313|EMBL:KEQ67824.1};
GN ORFNames=M437DRAFT_36423 {ECO:0000313|EMBL:KEQ67824.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ67824.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ67824.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ67824.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; KL584824; KEQ67824.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074W8A2; -.
DR STRING; 1043003.A0A074W8A2; -.
DR HOGENOM; CLU_007127_10_0_1; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF51; MANGANESE RESISTANCE PROTEIN MNR2; 1.
DR Pfam; PF01544; CorA; 2.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 766..789
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 801..822
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..49
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..114
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 829 AA; 93787 MW; 0B65CC828ABC6C66 CRC64;
MAKPKAPQKS YASALGEEAS STRDGTANST AGGSKKKRHR AGKKRRNRRQ SFAAPSESTA
AEREDDQNQR PTLTSNRPSA TQTSFYRLKS AARSNTSLES DALLDHRDHQ PIRPRRGSIQ
QPPRNSAGLY PRNHRSSHGV SQSSPVKPRH IQYSDDEDEE AVTDRTPLIS QSYYDRPPIE
RNRSGHRTYG GTRRRQSATS HTSSKRARYP SGSDDDYDVN NPPSMPGSPK LGTLNDVMIA
QEFSGSPSSE NRDAIINIDR DNNSDRHPSS SPPTPSAEAR RRTLANLAEN DVCYPGHIAE
SELGEDDLTP TDQGQRRTSR RRRHRQWPDL DVLDEWSRIE KEERDHTEQI RSKKISEPVM
VGGRLRPAKT QWHREEDDAP YRYTYFNETF DGTIHSRTIS ELCQFGATFR ELFNPEPPEL
SDDSSSEEED NPLPEAPSGR ESRLSSIAGD GKAPDRSASA TPAQSRPPRR PKEKRYGPRP
TFWLDVLSPT ETEMKILAKS FGIHQLTVED IMMQEPREKV ELFQSYYFVN YRSFEQDKDN
EEYMEPVNMY VVVFKDGVIS FHFSMTPHPA NVRRRIRQLN DYMSPTADWI SYAIIDDITD
VYAPLVQVIE DEVDEIDYEI LALHSSDENT DDKVKNSAKA KELEYEKMSK VAGSDTQSEK
GERTAGDSGG DMLRRVGNCR KKVMSLYRLL GNKADVIKGF AKRCNEHWEV APRSEIGLYL
GDIQDHVATM TGNLSHYENL LSRAHGNYLA QINIRMNERA EQTNDVLGKL TVLGTIVLPM
NIVTGMWGMN TKVPGQDGED LTWFWGLTAG LFAFGLISYF IAKRVYGIV
//
