ID A0A074ZJG9_9TREM Unreviewed; 574 AA.
AC A0A074ZJG9;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
GN ORFNames=T265_05750 {ECO:0000313|EMBL:KER27131.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER27131.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER27131.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KL596730; KER27131.1; -; Genomic_DNA.
DR RefSeq; XP_009169094.1; XM_009170830.1.
DR AlphaFoldDB; A0A074ZJG9; -.
DR STRING; 6198.A0A074ZJG9; -.
DR GeneID; 20319932; -.
DR KEGG; ovi:T265_05750; -.
DR CTD; 20319932; -.
DR OrthoDB; 3015718at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 445..574
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 574 AA; 65321 MW; 42E62805D46F0116 CRC64;
MCVTLCPAQT TLTIKPTSAS ASAFWTDKRG HYSRLSFGIA SWMRTFLIKT LLSLVVNAFI
QTELRCLRNY STITMTSALI VRPRFSGPAP YYFQAPTNKQ ITFQERNNAL HRGLFTPWES
EINSTSDVEE TPNESEMKMT KGRILSEAES SPHQPCPSSI WGLPGEQCGN SVVADNTISD
EKYAHEDEKI IALFQQRMLK QLNLKEPPKV TNSSWSSIPR FLQRQLQHTI EGHNHILEDP
VEQNEEKEVL VLLQPHPIQL RKIPSLAFTV KLVDYIDDRH ILRARIHAEA FRELPYGSEI
SLWEIVRPWP GSHTRHPKTQ SYDPWDETHV FLSGSGAQLS EDAYPDERGV TPFEDISVVG
QKVASALVYL DESDKVTSVT FNITSRLVQW IKHRNRMVLN GREKINHRPF VKHLLLICPT
CAGSQIPIDP RKVVMDIRYR AGLKRTKRAA GGSEEGLSNM CQDVGHQFTC CTQPLSIKFS
EIGWNKWIVF PKQVEPNYCR GSCQATGSRS SHYDILNLLH QKNSTRFPGV RRDELQSCCY
PTRRNSFSIL YMAGENDIRM HVLHNLIVLG CGCS
//
