ID A0A074ZMI4_9TREM Unreviewed; 626 AA.
AC A0A074ZMI4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|Pfam:PF00078};
GN ORFNames=T265_04832 {ECO:0000313|EMBL:KER28301.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER28301.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER28301.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR EMBL; KL596702; KER28301.1; -; Genomic_DNA.
DR RefSeq; XP_009167942.1; XM_009169678.1.
DR STRING; 6198.A0A074ZMI4; -.
DR GeneID; 20319014; -.
DR KEGG; ovi:T265_04832; -.
DR CTD; 20319014; -.
DR OrthoDB; 3295504at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01868; Rab11_like; 1.
DR CDD; cd00304; RT_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47979:SF33; DRAB11; 1.
DR PANTHER; PTHR47979; DRAB11-RELATED; 1.
DR Pfam; PF00071; Ras; 1.
DR Pfam; PF00078; RVT_1; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000054324}.
FT DOMAIN 401..532
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|Pfam:PF00078"
FT REGION 602..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 70321 MW; 8C439F59777641B4 CRC64;
MSWANRKGDE EYDYLFKIVL VGDSGVGKSN LLSRFVKNEF NLDSRSTIGV EFASKTVKCE
GKCIKTQIWD TAGQERYRAI TAAYYRGALG ALVVYDISKA QTFENVMQWL HELREHADPE
IVVMLVGNKC DLRFLRNVSV DDAKEFARRE RLFFIETSAL DSTNVDEAFE QIIYGRGQAK
AARRGPRKID WAAAKEVLAV EFDRLADRQE AMRRFMTARM VPGSDPTVFF AGLQQSLDRA
CRNWTECCAT SCSPSSSSKL SVEELVRLAR ELPEVPLATL QSQENRDGSI VDELQTRVDQ
LRSEGLLCFT SNAVVGSRFA DAGRSARHQL LSDQFVEGVQ PALGAQLRLA RATGQLSVEE
LVRLARELPE VPLATLQSQE NRDGSIVDEL QTRVDQLRSE GLLCFTSNED EILVSFDVTS
LFASVDLNAE RTTVAELLDN RGNINGTLGK EEICELLHLC LTTYFEFNGE YYEQIKGAPM
GSPISGLIAE ITMQKLERIV LPDIKPKIWV RYVDDTFAVV KKNELLRAEE LLNNVFPGIQ
FTMETEENNK LAFLDVLVTR TTNGQLQTEV XXXXXXXXXX XXXXXXXXEM SQAELCSNSI
QADRGTLQHN RGEEKGRTKT LRDIPK
//
