ID   A0A074ZUX3_9TREM        Unreviewed;       505 AA.
AC   A0A074ZUX3;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=HORMA domain-containing protein {ECO:0000259|PROSITE:PS50815};
GN   ORFNames=T265_05762 {ECO:0000313|EMBL:KER27150.1};
OS   Opisthorchis viverrini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX   NCBI_TaxID=6198 {ECO:0000313|EMBL:KER27150.1, ECO:0000313|Proteomes:UP000054324};
RN   [1] {ECO:0000313|EMBL:KER27150.1, ECO:0000313|Proteomes:UP000054324}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA   Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA   Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA   Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT   "Opisthorchis viverrini - life in the bile duct.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KL596730; KER27150.1; -; Genomic_DNA.
DR   RefSeq; XP_009169106.1; XM_009170842.1.
DR   AlphaFoldDB; A0A074ZUX3; -.
DR   STRING; 6198.A0A074ZUX3; -.
DR   GeneID; 20319944; -.
DR   KEGG; ovi:T265_05762; -.
DR   CTD; 20319944; -.
DR   OrthoDB; 2915579at2759; -.
DR   Proteomes; UP000054324; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.900.10; HORMA domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR003511; HORMA_dom.
DR   InterPro; IPR036570; HORMA_dom_sf.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR48225; HORMA DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR48225:SF7; MEIOSIS-SPECIFIC PROTEIN HOP1; 1.
DR   Pfam; PF02301; HORMA; 1.
DR   Pfam; PF20826; PHD_5; 1.
DR   SMART; SM00249; PHD; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR   PROSITE; PS50815; HORMA; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          1..223
FT                   /note="HORMA"
FT                   /evidence="ECO:0000259|PROSITE:PS50815"
FT   REGION          246..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          448..468
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..265
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        448..466
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   505 AA;  56764 MW;  CA21A0D667BD5819 CRC64;
     MSSIPGAYSR ILHFLISSWK VGQNQSFYTV RCEVENTQRR QQISWVVESC LLVAWLLRCH
     RSAIRRLTLR NITTLQLKSA LISLYCRDEA KRSSVNIYDS CKIVESYSFK LAYGESAVEV
     DGAAGDNLVS RSRLLPPAVS QAEIQTATIN LLKTINAVGE KAKRLSGDLF MTMRLQYTDD
     TPEDYVPPGF KKADDVVFQF DGIPANIRVG IVKTAHHSLK MHLQTNRAFL PLTKHLNEDK
     MEIQEASQKS LELKNQPQPE QQIPDSKETD LTESLQKQTL QSEDDSEETF SVRCPCGVNK
     DDGVMILCDG CGMWQHAVCF RILEETDVPS SHICEKCSET KPELLQKGGI TDNSLKGLPD
     DARKSLCLLR RAVLLCTSLD SISPAIISKN LEVKYTVARS LFNRLIDEGI LKEVGSKRGE
     KMVDKNYLEE TVILKIFQHS SVEINGTSSF EPRSQFGHSA SSPPRSVRHT PRLFEASQDS
     IFSPVPPRKR RRTGIANTPV AIFRR
//