ID A0A074ZZL3_9TREM Unreviewed; 897 AA.
AC A0A074ZZL3;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
DE Flags: Fragment;
GN ORFNames=T265_13523 {ECO:0000313|EMBL:KER28705.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER28705.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER28705.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL596693; KER28705.1; -; Genomic_DNA.
DR RefSeq; XP_009167554.1; XM_009169290.1.
DR AlphaFoldDB; A0A074ZZL3; -.
DR STRING; 6198.A0A074ZZL3; -.
DR GeneID; 20327690; -.
DR KEGG; ovi:T265_13523; -.
DR CTD; 20327690; -.
DR OrthoDB; 277036at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15734; FYVE_ZFYV1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR015894; Guanylate-bd_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR042427; ZFYV1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46624; AGAP002036-PA; 1.
DR PANTHER; PTHR46624:SF4; ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN; 1.
DR Pfam; PF01363; FYVE; 2.
DR Pfam; PF02263; GBP; 1.
DR SMART; SM00064; FYVE; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50178; ZF_FYVE; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 735..775
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 836..896
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 338..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KER28705.1"
SQ SEQUENCE 897 AA; 99298 MW; 9AAD05A1493D597C CRC64;
DPREKLARWA LRLQEYDFTI QHVPGKENHL ADWLSRPEAE NEVPKIMIGA NVLVVELDPG
KLVQLQRQDP VLQKVAAALL DGRNIENGEG DKMSYDNPIL RTAQSVDAPP VSVVRKGRQT
ATAPPYTQKP HCDVNDPPGL PVSTDSRVAY HNLVDGMNGP RSVQLVNEEE KLNFDDCESF
AAELGCPMDQ LLKVVAIVGN TGDGKSYTMN HTFFDRAEVF LTSSSQCTCT TGVWAACAPS
QNCLVLDTEG KCLLGTTLNQ NQHRRLLLKV FAVADIVIYL TKAPRLHADM FTFLADASDS
FAQHFRPELE TLAKQNRLPW SHGQLGPAVI VFQETRHTDP LDGPKVDGKP TPYHRNEGSN
PLKDSDENNP VTSVLQHRIA EMNRNVDSFS TLEYIGIQTT DCETNFERLK QSIARLLKDN
SIRAPRKLEH IFYSLQSLNA QFAGSIRPNG QYTFVEEYFT CPVQCDVCSI RCCLGVGHTK
QPHQASMNTS ADGSERKANP AGCRYDPSLK NKLYYCKDCY AEGKRNMVVP KAGESMLDAP
RYFYSGYVLE CKVHGTIYQS RNLWSSNEEP ERTARVHWEV VHVWSGEKTV LQGIHTFSQV
LVDGVNSVTK HITGLAAPPA RFIGDYLADS MAPDYWVPNA NIRNCAVCNF KFPDPLVDGA
DFDLGTRPQQ QQQKQQGKVE SDGGRSRPKS KSHRSSIAAP SSRAPPVPDD NTASHTSPEH
HASSVPDLSS LDVAKHHCRM CGRGVCGACS SKRLRVPGFG LDPVRVCDDC FGRHNGGPKT
TSKSVAKDIQ VESNTGYTGR RALELCSAAV RSITPVVNFV TGTAKDFARP AYWTPDNLCK
YCAVCDQPFN ASRLIHHCRA CGRGVCEPCS GHRMPVPWRG LDLPHRVCNE CFKPAVQ
//
