ID A0A075A1Z1_9TREM Unreviewed; 1725 AA.
AC A0A075A1Z1;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Low-density lipoprotein receptor domain class A {ECO:0008006|Google:ProtNLM};
GN ORFNames=T265_01685 {ECO:0000313|EMBL:KER32257.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER32257.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER32257.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL596636; KER32257.1; -; Genomic_DNA.
DR RefSeq; XP_009164015.1; XM_009165751.1.
DR STRING; 6198.A0A075A1Z1; -.
DR GeneID; 20315873; -.
DR KEGG; ovi:T265_01685; -.
DR CTD; 20315873; -.
DR OrthoDB; 2969152at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR CDD; cd00112; LDLa; 6.
DR Gene3D; 2.40.128.620; -; 2.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 4.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270:SF66; CUB AND LDLA DOMAIN, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR Pfam; PF00057; Ldl_recept_a; 2.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00192; LDLa; 6.
DR SUPFAM; SSF57424; LDL receptor-like module; 4.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000054324}.
FT REGION 375..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1158..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1318..1338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1518..1560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1610..1635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1181..1195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 219..234
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 279..291
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1002..1017
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1062..1074
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 1725 AA; 189282 MW; 7E61BB08D00345B4 CRC64;
MCAVSVKNFV LFILPFVGQR HTVLSRPALE YNEIVSQCHG VIEYLAPALS TPIVKGWLLS
PGYSSSHGLM HGSPYSPPHR HRSEQPRLIR LRMEHLKLPE GFQLVVRNLG SEEPSDAVFY
TGVQNKIELS VAGTPVQIEL RSPRLSDDLH KDVDDLLHVW IQHSCVHAEP TTLEGSHLGL
QTCSNPISTL LEQNTELACR SRSVGTISEV RCIQQSQLCD EVKDCQYGED ELVCDSQQYT
EERVLTFLSQ THNAPSYHTP FFMHQHLLKT GCLFEWDACF MSELRSHSMV CIPSAWMCDG
QHDCPNGEDE LPETCSRVQG TKCPAQTYPC VLDARCVSHQ LICDGYTDCL LGSDETEQAC
DWKATIAVQL DRERDSNRLN GETPKSVGSG ERVGPRDLSD NSVSTISVNS GHSVRRRVDT
RITQTPQVTE AEVSINDVLL KTTGLVTTYG PHSRNNLTFP GSSISVTEMN LTEVPSDYDT
STVLPYKTNQ GTVSPRSDRL QEALSTTFAP VSRFAVSSSI KPIADRVIHR PIAATNDQQH
ETTDRTFSSE SAPNFATSTT EGFRIELVSN ISESDTQANV TDGFTGASAN LPTESSKNKT
TRKAITGVSA LVDLTSTEIV GIPAETGIIL SRPALEYNEI VSQCHGVIEY LAPALSTPIV
KGWLLSPGYS SSHGLMHGSP YSPPHRHRSE QPRLIRLRME HLKLPEGFQL VVRNLGSEEP
SDAVFYTGVQ NKIELSVAGT PVQIELRSPR LSDDLHKDVD DLLHVWIQHS CVHAEPTTLE
GSHLGLQTCS NPISTLLEQN TELACRSSRP ALEYNEIVSQ CHGVIEYLAP ALSTPIVKGW
LLSPGYSSSH GLMHGSPYSP PHRHRSEQPR LIRLRMEHLK LPEGFQLVVR NLGSEEPSDA
VFYTGVQNKI ELSVAGTPVQ IELRSPRLSD DLHKDVDDLL HVWIQHSCVH AEPTTLEGSH
LGLQTCSNPI STLLEQNTEL ACRSRSVGTI SEVRCIQQSQ LCDEVKDCQY GEDELVCDSQ
QYTEERVLTF LSQTHNAPSY HTPFFMHQHL LKTGCLFEWD ACFMSELRSH SMVCIPSAWM
CDGQHDCPNG EDELPETCSR VQGTKCPAQT YPCVLDARCV SHQLICDGYT DCLLGSDETE
QACDWKATIA LQLDRERDSN RLNGETPKSV GSGERVGPRD LSDNSVSTIS VNSGHSVRRR
VDTRITQTPQ VTEAEVSIND VLLKTTGLVT TYGPHSRNNL TFPGSSISVT EMNLTEVPSD
YDTSTVLPYK TNQGTVSPRS DRLQEALSTT FAPVSRFAVS SSIKPIADRV IHRPIAATND
QQHETTDRTF SSESAPNFAT STTEGFRIEL VSNISESDTQ ANVTDGFTGA SANLPTESSK
NKTTRKAITG VSALVDLTST EIVGIPAETG ISMPTKAAAK TSAVSSELFH NIISFTEQSV
YDGLLPQVAA NRSSNQGITE VTETISPVTT SDMSLMTKSA HKMTSGIELD TFPVASPSTE
MVSTEPGTTE KVTTSVYLSN SGEDGNTRGA SRSGLPDTER NINPGVPSAF QEVTPSSKPL
EQEIRKVTSS AGKFNNEQGT SVREFFTVRK VTSSAGKFNN EQGTSVREFS QTEMRDKNQS
INSEVPTSTE QNTPGEVTHS NGVIGMQPHT PLKLPSPNRW SKTGGVATRK ITTHLFVDEP
PDLGLPGRLA KLSHSSEVEQ RKASLNGLPN MELNVAKREF SFDEP
//
