ID A0A075AFH7_9TREM Unreviewed; 1958 AA.
AC A0A075AFH7;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KER27749.1};
GN ORFNames=T265_13733 {ECO:0000313|EMBL:KER27749.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER27749.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER27749.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Nucleus membrane
CC {ECO:0000256|ARBA:ARBA00004232}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004232}. Rough endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004269}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004269}.
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DR EMBL; KL596715; KER27749.1; -; Genomic_DNA.
DR RefSeq; XP_009168502.1; XM_009170238.1.
DR STRING; 6198.A0A075AFH7; -.
DR GeneID; 20327900; -.
DR KEGG; ovi:T265_13733; -.
DR CTD; 20327900; -.
DR OrthoDB; 2882564at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030867; C:rough endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0023041; P:neuronal signal transduction; IEA:InterPro.
DR InterPro; IPR019130; Macoilin.
DR PANTHER; PTHR13289:SF6; MACOILIN; 1.
DR PANTHER; PTHR13289; PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL; 1.
DR Pfam; PF09726; Macoilin; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 501..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 231..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1149..1198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1295..1355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1407..1435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1561..1596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1672..1748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1914..1958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 960..977
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1007
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1085..1134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1295..1309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1316..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1414..1431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1582..1596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1672..1722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1733..1747
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1914..1930
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1958 AA; 216010 MW; 7C739254AF93A9C0 CRC64;
MFTINGNTTI HSNEIKDLGL RYSCAFRFSY QVQFHVARAR RLCFLILRSF YLHDPKVAIS
KLCVRSCAKS RSAFSFFCRR ALEKVQRPFA KMSSSQTCPL SYRFRCMIVA LEPLWLRRSK
LNLTLRLGQT WPYTRYTFVC PQARTNTRHQ FFLVYYTRVR NSLRDRFRNI TQQRTFSQLV
DNSLACEAAA ALLNTHIPQH ARGMKASCGG RPAGGVFLLC CTMERSHAHY PTGSKDASPI
AAHLPPSRRR CQSNDHCFVA STSIKRVLAL ELQNFKPPAK LSVDLESVRK VSDVYQNKKK
RSRKGALRST LNTGAREQNY AVEKAGAIQQ NQESIGRHSA FWQAPLRMIG RTFSRIRSTS
FWQAPLRMIG RTFSRITRMD FQILYGWCAN QVVHSGPSRQ ENGCRPQTVN YETRLAVLDL
FPLDYRRLRG DLILTYALFE QSLAKSFLPL TEQSHDGDIV RKFSSSGHTH SLEKIFFISG
TAWNDLPLTV VHAPSRTQFK ALLEILFMRI LALAILLTLR GAVCLPRAEN IKCSATPFFH
LCLSGERQPL TDKNKPDPGN LDKNLDPVYQ SVNPFGTPFK LLIIWATILM LDFFTDFRFE
FIYSCWLFVR TVIDSFRYQG LAFALFFTLI ATMSDVVCYF LVPTTLVYLL GSSFVWIQLV
WQSAHNSSSE CSSRYAESKR SLNCSTLSVL TVLSSKGSTR AGILPGCPSL DRRSREAEVG
FESWTFRSVN SRFKHSHLTQ FVLRCTIYFG SRWLKWLERE FTDRKVRGSN RTSAIRLPLS
RLGRPGSIPA LVLPSDGMAG RHPKGATAER FIIFIYISVI CVRCSLGPDF TPVHILLLSD
RGFYAPTIVL CFIFVYVEVA VRLRDPKHIP LGIDICRPFA THCVGYPAVT FGFVLKTMVS
HHFRQRRQRS VETQNATFFA LLEEALPKEL RQYLKTDGSS PKSNRSLPSP PDVRPALPAS
SSILPSTNRS VSSKDKVGVS APSGRKQASG GLKLDPNLSS LSSCSPDVLR PPVTEGSNRP
VVFAQHNDST HLGNLALPES ISSQIALSET DNVEKSDDTI AASPNTLWRT ADQIDLEFSF
DDQASGHQLG DSEQNGQTIQ APKAPSSVSS TTSTSSSSST CSSSSSSSLF VTGHPSRSVL
STLGERLNEA KQSTTGGTDL ANSSSMAKSS VSTTNPTNTA STVKSTGKSG SLQGTSSKNA
TKDEYTLKLE VELKQLRTEL HTLRGLEVDL RAQVQQLTAA ERTFRSESSL ARQESETLQA
KMMQLTQRLE TDRANLRSTE ERLLEERKQR VALEQRLSAQ QQSRQNAHKS PKDTSTDDTP
SQTASKTSCA KSTTAPPRNT SSPGANNNSS SSALAGSSST VATTFTQTTA SCTATDSCAT
RVKELEAELR TLKRDLSDRE AQLATLKESR AAHGVNGSDS TTCGKKGSMT NRLQDDSAER
EELLSHLAHL QEENQRMTDT LKDEDKMKQE LLTAYHASLK EITELNASLT KKEFQIVELN
MRLESLTPHL YEYVNMINVA SKHLSSASHL PLETNSSEQG GYSVFSSDML PRYTNSVASA
TAKGQHNLRK SPPDDHSFSD GRSAHTPANG LSSSSTSGYF GSSLEYPTST YGSSFVDSMG
LRNLSRINST TVTTMETTPH SPMTNGGGRM YHTFSNRTFL SAADSATVNH VYSSTQSSQA
PSYTRQSPRS STNHTHFNSS HFDLSSYPQH NRFKSSVSPY PGSGTRPLPV GSAAPASSPP
PFLVPPPGLI HNSVNPTLMH PSTVASDPHP FSSSHPTNRP LEVIVNAPGS MQSDLFHSPV
CLDIGGQSSS PCASSSVNRL IESLSLFGSS SDSGSFVHPG RRMAADSFSA NTTTDASMLY
PHPDATSIVQ MNATTRAPHS YRLRGTYDDV DLMDTNELNL MGLNVLDTSV LKSDGSATDG
STSLQPTADD RVTGKNLDAD GFGHLQSGHS LSDRNSAM
//
