ID   A0A075AIL7_9TREM        Unreviewed;       410 AA.
AC   A0A075AIL7;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   22-FEB-2023, entry version 21.
DE   RecName: Full=VOC domain-containing protein {ECO:0000259|PROSITE:PS51819};
GN   ORFNames=T265_01945 {ECO:0000313|EMBL:KER31854.1};
OS   Opisthorchis viverrini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX   NCBI_TaxID=6198 {ECO:0000313|EMBL:KER31854.1, ECO:0000313|Proteomes:UP000054324};
RN   [1] {ECO:0000313|EMBL:KER31854.1, ECO:0000313|Proteomes:UP000054324}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA   Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA   Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA   Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT   "Opisthorchis viverrini - life in the bile duct.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC         Evidence={ECO:0000256|ARBA:ARBA00001962};
CC   -!- SIMILARITY: Belongs to the 4HPPD family.
CC       {ECO:0000256|ARBA:ARBA00005877}.
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DR   EMBL; KL596640; KER31854.1; -; Genomic_DNA.
DR   RefSeq; XP_009164347.1; XM_009166083.1.
DR   AlphaFoldDB; A0A075AIL7; -.
DR   STRING; 6198.A0A075AIL7; -.
DR   GeneID; 20316133; -.
DR   KEGG; ovi:T265_01945; -.
DR   CTD; 20316133; -.
DR   OrthoDB; 2898711at2759; -.
DR   Proteomes; UP000054324; Unassembled WGS sequence.
DR   GO; GO:0003868; F:4-hydroxyphenylpyruvate dioxygenase activity; IEA:InterPro.
DR   GO; GO:0009072; P:aromatic amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 2.
DR   InterPro; IPR005956; 4OHPhenylPyrv_dOase.
DR   InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR   InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR   InterPro; IPR037523; VOC.
DR   PANTHER; PTHR11959; 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE; 1.
DR   PANTHER; PTHR11959:SF10; 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN; 1.
DR   Pfam; PF00903; Glyoxalase; 1.
DR   SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR   PROSITE; PS51819; VOC; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          187..350
FT                   /note="VOC"
FT                   /evidence="ECO:0000259|PROSITE:PS51819"
SQ   SEQUENCE   410 AA;  45313 MW;  BA37963F32EC0325 CRC64;
     MSLIRRVHHL QFACQNLWNM CRAFSNGLGF KIHSFMRHEN RYSVALGNGS CMLLLNQTTG
     PPIHWRIQPS ELSQKLTDSY AHRQMPFDIA LEVQDVSDVC TRVRHMKGTD WVLVEPLVCS
     DNHGRITMAV IKSCIKNLFH TLLDTSQYDG PLLPGFTLPE VDVAPEIAQE VQQYTVHPDC
     PSPVFGHLDH IALACNTGES DPIIQWYKEV FGMKRVAANI LDDPNDGFLV EYGHTGMKLK
     AASYTETLTD ACTFVLVEPL EGSAPNQVTR FLDANGGPGI QHIGFAVDDI FTAVDSCKAR
     GTSFVTPPQS YYDAISQIPA FARCPVNIKQ LRQSGVLLDP DISPDQSGSE DPVMLLQIFT
     MPLFERDAFF VELIQRCGGA SGFGAGNILA LWKALEDSIA SGDQQQQNPG
//