ID A0A075JVQ7_9BACI Unreviewed; 2585 AA.
AC A0A075JVQ7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Gram-positive cocci surface proteins LPxTG domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=X953_16860 {ECO:0000313|EMBL:AIF45590.1};
OS Virgibacillus sp. SK37.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX NCBI_TaxID=403957 {ECO:0000313|EMBL:AIF45590.1, ECO:0000313|Proteomes:UP000027985};
RN [1] {ECO:0000313|EMBL:AIF45590.1, ECO:0000313|Proteomes:UP000027985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK37 {ECO:0000313|EMBL:AIF45590.1,
RC ECO:0000313|Proteomes:UP000027985};
RA Phrommao E., Yongsawatdigul J., Rodtong S., Steele J.L.;
RT "Complete genome sequence of Virgibacillus sp. SK37, a moderately
RT halophilic bacterium isolated from Thai fish sauce fermentation.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC {ECO:0000256|ARBA:ARBA00004168}.
CC -!- SIMILARITY: Belongs to the serine-aspartate repeat-containing protein
CC (SDr) family. {ECO:0000256|ARBA:ARBA00007257}.
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DR EMBL; CP007161; AIF45590.1; -; Genomic_DNA.
DR RefSeq; WP_040956481.1; NZ_CP007161.1.
DR STRING; 403957.X953_16860; -.
DR KEGG; vir:X953_16860; -.
DR HOGENOM; CLU_225708_0_0_9; -.
DR OrthoDB; 2056845at2; -.
DR Proteomes; UP000027985; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005518; F:collagen binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00222; CollagenBindB; 12.
DR Gene3D; 2.60.40.1280; -; 2.
DR Gene3D; 2.60.40.740; -; 5.
DR Gene3D; 2.60.40.1140; Collagen-binding surface protein Cna, B-type domain; 12.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR InterPro; IPR008454; Collagen-bd_Cna-like_B-typ_dom.
DR InterPro; IPR008456; Collagen-bd_dom.
DR InterPro; IPR011252; Fibrogen-bd_dom1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR041033; Prealbumin-like.
DR InterPro; IPR041171; SDR_Ig.
DR PANTHER; PTHR36108:SF13; COLOSSIN-B; 1.
DR PANTHER; PTHR36108; COLOSSIN-B-RELATED; 1.
DR Pfam; PF17961; Big_8; 2.
DR Pfam; PF05738; Cna_B; 12.
DR Pfam; PF05737; Collagen_bind; 5.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF17802; SpaA; 4.
DR SUPFAM; SSF49401; Bacterial adhesins; 7.
DR SUPFAM; SSF49478; Cna protein B-type domain; 16.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000027985};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2558..2578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 60..148
FT /note="SDR-like Ig"
FT /evidence="ECO:0000259|Pfam:PF17961"
FT DOMAIN 271..362
FT /note="SDR-like Ig"
FT /evidence="ECO:0000259|Pfam:PF17961"
FT DOMAIN 390..514
FT /note="Collagen binding"
FT /evidence="ECO:0000259|Pfam:PF05737"
FT DOMAIN 534..636
FT /note="Collagen binding"
FT /evidence="ECO:0000259|Pfam:PF05737"
FT DOMAIN 667..753
FT /note="Collagen binding"
FT /evidence="ECO:0000259|Pfam:PF05737"
FT DOMAIN 799..914
FT /note="Collagen binding"
FT /evidence="ECO:0000259|Pfam:PF05737"
FT DOMAIN 935..1053
FT /note="Collagen binding"
FT /evidence="ECO:0000259|Pfam:PF05737"
FT DOMAIN 1093..1159
FT /note="Prealbumin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17802"
FT DOMAIN 1190..1256
FT /note="Prealbumin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17802"
FT DOMAIN 1281..1352
FT /note="Prealbumin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17802"
FT DOMAIN 1379..1446
FT /note="Prealbumin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17802"
FT DOMAIN 1461..1542
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 1547..1627
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 1635..1725
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 1732..1813
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 1820..1900
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 1908..1989
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 1997..2079
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 2087..2167
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 2173..2255
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 2261..2342
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 2348..2428
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 2436..2517
FT /note="CNA-B"
FT /evidence="ECO:0000259|Pfam:PF05738"
FT DOMAIN 2544..2581
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|Pfam:PF00746"
FT REGION 138..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2520..2549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2585 AA; 288980 MW; FAE2207381465D2F CRC64;
MQRRLSMLFI CVLLFQTMIS GIAPSLVKAE GKQQSIFTDS MLTDEEGNTV TLEEVKAGAP
VHIHIGWSVK DKDIQADSNE TLQLPADLEL SDSQEGELGK DGNVIGTYKA ITDGALTVQF
SEAVKDYPDS SGTIVLSTVK SKESTKEKEQ DASEDAPEGE KETSSSVTGK KENTTSEQVT
EEGKETEKQN PDKQDEAMNT EEPNTNSTNE TADIGSSDEE KDVKKVVKED TETEKGSVQS
TAKEAHGFNL VLDAVTDLDG NPYTEDSLLE PKDQFQLKLD WNLENGHTYT AGDKQVFQLP
KGIKITEEMT GELKDASGLT VASYKITTDK KVELTFTDYV ETHSNVKGWL QIISQLDEEN
VDVEDGEAII EPIGEEGEIR IPIVQGNTEK TIEKKGTPNK GYNADEINWE VKINKHKTSL
TNAKIKDILP EGTEYKEGSL KVTKLKVDLY GNVLGDAEEV DVTGETFVNG ELSIPLGNIK
DAYRVEYATT VTDDEKKEFT NNAILSDDEL EDISAKSTVT IDRGEAIKKT AAKSYNPKTG
IIEWEIEFNY NEKNLEDVTL KDAWTPEGKM DLVEDSLKFT EVTIDENGKA HPTDNVGLPE
GAKLVPGTDQ FEVTGITTDK SYKVTYQTKV KDRVLDPFEV ANTAGFGTET DGSTTGVGTY
YGSKSAGTID YKNKTIDWKI EVNHDEYPME KISIKDTLGE GLTLKEDSLK VTVDGKVYEG
DYTLLGDNPF TIQFPNDFTT DKKIVITYET SYVADEVPEQ KPTNTAAITW TPEGGSDSIT
KEVTAGTELN DNTKNNDWKN GSYNPETKEI TWTIYTNYRE NTIENLIVKD APQGNQKIVA
DSVVVKELAI DKKGNITEGD QLTDSISVDI ENNTFQVTIG ETNKAHKIEY KTSLAGLSDI
QKEYVNKAEV LDGENNKLSD LDAKVSIAKS DTYGEKSGGQ DGKQVHWSVN VNLGQQKINN
LKLVDTISAN QEYLTDTIKV YEASVDKDGK ASKGEELSTE QYELTHTPGE LDFTITWKNE
VERAFIVEYS TLFFEKHNGE VTNQYSVTGD NIVEGGQTDG GGKVTIKQLA SGGGSGEAGY
FVIDKVDTTY GKEETSLEGA EFDLIDADTG NVLKTGTTDE NGQIDFGRLL FGEYELHERV
VPDGYVTKNE RQTIVIDEKY EQNNEQTKTT YRVENFVPVY AIELLKTDNK GKALQDTEFT
LYDGDKKELT KATTDQDGKI LFEDLKEAGT YYVQETKAPK GFVLDSTEHK VVIGDKEPEP
VKVSIDNQPR GAVILTKKDL DSGAALEGVE FVLQKQDDRG DYKTIATLTT NDNGKISTSN
TLEAGNYQFV ETKGLDGYRT NGTPIKFTVN VNSTKDQQFT MKNERYKGSI KLVKKNDVTD
ATLKNATFKL LNANGELVEE NLTTNNQGEL QINDLFLGKY QLIETKAPAG YRLDETPIDI
EISEDNQVIE KVMTNEKITN ITVEKKWNNS SGDTESVTVK LLPTDQTVKL NEGNDWKATF
KDLSVYDEAG EVIDYQVEEL KVDGYNSAVT GDRVNGFIVT NTETTSVSGT KTWLDDESAD
RPDAITVKLF ANGEKVATTE AKAANDWKYS FKDLDKYDAN GEEIAYTIEE VPVEGYETTV
NGFDLENLRV GTVSVKGEKI WQDEDPTDRP DEITVNLKRN IDGVEDKSFS KNKTVKPNNQ
GKWVYTFTDL AEFDEHGAAY TYTVKETNVP EKYEAKIDGY DIINTRVGTT EVSGKKRWKD
DKITDRPETI TINLLRNNVV VDTTQTTADD EWVYRFQDLP KYDNQGQLYD YSVKEQDVKG
YDSKVSGFDI TNTRAEKKSI EVTKGWLDDN SKDRPTSIIV YLKQNGELFD TVQLKAEDDW
TYVFNDLEAY DENGQEYAYT VKEKALEGYE TKIDGFNITN LRVGKTEVTG TKTWLDDNSP
DRPESITVKL LANGEETDKT ITVDANSDWK YAFTDLEKYD DQGKEIAYTV DEEAVEGYKK
TISNNNITNL RVGKTAVTAE KIWNEVDKRY RPDHVTINLL ANGEVIDTQI VTADTDWMYT
FSDLEKYDEQ GKEITYTVEE NDVPAGYDVD IDGYKITNTQ KSTEVIGTKE WIEVDERYRP
DSITVQLLAN GEKEATVEVS ENTNWTYAFT NLAKYDKAGE EITYTVEELD VPTGYKSTVD
GFNITNTQKT TEVTGEKTWV EVDERYRPDS ITVQLLANGE KETTLEVSAE TDWKYTFTDL
AKYDKTGEKI TYTVEEINVP TGYETEVDGY NITNTQKSTE VAGEKTWKEV DERYRPDTIT
VNLLANGVVE QSAEVSKDTD WTYTFTDLAK YDKEGNLITY TIKEDAVTGY TSTVSGHDVT
NTQQTTEVSG MKTWLDDESA DRPDIITVQV KNGEEIVQSQ EVTADNDWSY TFKDLPKYDK
AGKEINYSIN EKAVDGYKTI INGFDITNLR ANVTVVEGEK IWKNDRPAER PEAITVILYA
NDKELKRQKV TKEMDWKYTF ASLQQFDDEG KAIVYTVGEK PVDGYDTEVN GFTIINTWKP
NDPITPNDPE DTNNPVQPTI SGGTNNSGNE LPNTATNIFN IFMIGAGFLL AGFALWIYKR
KFARD
//
