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Database: UniProt
Entry: A0A075TZV8_9CORY
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ID   A0A075TZV8_9CORY        Unreviewed;       570 AA.
AC   A0A075TZV8;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-SEP-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=CATYP_00005 {ECO:0000313|EMBL:AIG63362.1};
OS   Corynebacterium atypicum.
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=191610 {ECO:0000313|EMBL:AIG63362.1, ECO:0000313|Proteomes:UP000028504};
RN   [1] {ECO:0000313|EMBL:AIG63362.1, ECO:0000313|Proteomes:UP000028504}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R2070 {ECO:0000313|EMBL:AIG63362.1,
RC   ECO:0000313|Proteomes:UP000028504};
RA   Tippelt A., Mollmann S., Albersmeier A., Jaenicke S., Ruckert C.,
RA   Tauch A.;
RT   "Complete genome sequence of Corynebacterium atypicum DSM 44849:
RT   identifiction of the mycolic acid biosynthesis genes.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP008944; AIG63362.1; -; Genomic_DNA.
DR   RefSeq; WP_038603882.1; NZ_CP008944.1.
DR   EnsemblBacteria; AIG63362; AIG63362; CATYP_00005.
DR   KEGG; cax:CATYP_00005; -.
DR   KO; K02313; -.
DR   Proteomes; UP000028504; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028504};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028504}.
FT   DOMAIN      260    388       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      472    541       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     268    275       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   570 AA;  62727 MW;  B0C33414A2917F81 CRC64;
     MADDRLALEE TWREVVAELI GASDRPESDI PTLTHKQRAF LALAKPIVLI NGYVLLATPH
     QMAKLVIENE LGECITRVLS ERMHRTCSLA VSVDPQASAQ ATPQAAAPAA SQAPDPAPRG
     APDAPSEPPA EPAYEGDFGA DPNRAFGADP QHHAPAHQPN AQAESQHAYP GVSADAPVSG
     AARHYAPGDA PRGVDNRRQG PSWEDSFARS PRLPREQPAH DPDRETSLNP RYTFESFVIG
     SSNRFANGAA VAVAENPARA YNPLFISGGS GLGKTHLLHA AGNYAKVLQP SLRIKYVSSE
     EFTNDYINSV RDDRQESFKR RYRNLDILMV DDIQFLQGKE GTQEEFFHTF NALHQANKQI
     ILSSDRPPKE LTTLEDRLRT RFQAGLIADI QPPDLETRIA ILMKKAQADG TRVDREVLEL
     IASRFESSIR ELEGALVRVS AYSSLIKQPI DLHNAEVALR DILPDPQDVV ITASAIIETT
     AEHFNLSVAT LCGTGKTRAV AHARQLAMYL CRELTDLSLP KIGDQFGGKD HTTVMYADRK
     IRKEMTEKRD TYDEIQLLTQ KIKNAGRGLL
//
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