ID A0A076MR38_AMYME Unreviewed; 274 AA.
AC A0A076MR38;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:AIJ21406.1};
GN ORFNames=AMETH_1314 {ECO:0000313|EMBL:AIJ21406.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ21406.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ21406.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ21406.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009110; AIJ21406.1; -; Genomic_DNA.
DR RefSeq; WP_017987267.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076MR38; -.
DR STRING; 1068978.AMETH_1314; -.
DR KEGG; amq:AMETH_1314; -.
DR PATRIC; fig|1068978.7.peg.1384; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_062618_6_0_11; -.
DR OrthoDB; 8479143at2; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF35; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000062973};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..82
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 83..265
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 274 AA; 29406 MW; 7756B9B9888B0A08 CRC64;
MTTKSTAGRK LAPANDNTGT EAAARVADVL LLFAGGPRYL GVSAISRELG LSKAVVFRIL
QSLVSRELLA TDPGVNGYRL GQAAAALGAS ALRRFDARTV ATPILRRLRD ETGETTTLSG
LVGDERVYLD QFESPREIKM TVDIGRRFPL HAGSSGKVIL AFLPEDRQES VLRRTLEPLT
DKTITDVDAL RTALAETARE GVAVSLGERQ AGAGSVAAPL FGPDGEVHGS ISICGPQYRF
TPEAIDRYRG LIRAASEEIR DNWTWLRDSE AGSA
//
