ID A0A076MS44_AMYME Unreviewed; 617 AA.
AC A0A076MS44;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN Name=celD {ECO:0000313|EMBL:AIJ23494.1};
GN ORFNames=AMETH_3402 {ECO:0000313|EMBL:AIJ23494.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ23494.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ23494.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ23494.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
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DR EMBL; CP009110; AIJ23494.1; -; Genomic_DNA.
DR RefSeq; WP_038532180.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076MS44; -.
DR STRING; 1068978.AMETH_3402; -.
DR KEGG; amq:AMETH_3402; -.
DR PATRIC; fig|1068978.7.peg.3636; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_004542_9_3_11; -.
DR OrthoDB; 9803863at2; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000062973};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..617
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001715976"
FT DOMAIN 59..374
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 413..614
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 617 AA; 65778 MW; 89EAF1F537BBB4C2 CRC64;
MRPRSVRRKT LFAVLAATVA LVSGATTVSA APVQHRPAYL DTGKPVPVRV ADLLSRMSLD
DKLGQMTQAE RGAITDPADI ATHRLGSLLS GGGSVPTPNT AQSWADMYDG FQRAALTSPL
RIPIIYGVDA VHGHNNVHGA TIFPHNIGLG ATRDPKLVGR IGGAVAEEVS GTGVDWDFAP
CLCVARNDRW GRTYESFGET PELASSMTTI IDGLQGRSSS DKGSILATAK HYVGDGGTTG
GVDQGDTELT EQQLRAIHLP PFRAAVRRGV GSVMISYSSW NGVKMHANRY LITDVLKGEL
GFSGFVVSDW QGIDKIDGQE GFTAEEVRTS INAGVDMVMV PYDYVSFIDT LRAEVQAGRV
PMSRIDDANR RILTKKFQLG LFERPFTDRR YTATVGSAEH RALARQAVRE SQVLLKNDGG
VLPLGKNGQK IFVAGKNADD IGNQSGGWTI TWQGSSGPIT PGTTILQGIR DKARSSAVTY
DRNGAGIDGS YDVAVAVVGE TPYAEFMGDR PAGMGLDAED LATLRRLKGS GVPVVVVLVS
GRPLDIAAEL PGWDALLASW LPGTEGGGVA DVLFGDYNPA GKLPVTWMRS AAQQPINVGD
GQDPLFPYGY GLRYRRG
//
