ID A0A076MU97_AMYME Unreviewed; 555 AA.
AC A0A076MU97;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Medium-chain fatty acid-CoA ligase {ECO:0000313|EMBL:AIJ22471.1};
GN Name=fadD9 {ECO:0000313|EMBL:AIJ22471.1};
GN ORFNames=AMETH_2379 {ECO:0000313|EMBL:AIJ22471.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ22471.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ22471.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ22471.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009110; AIJ22471.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A076MU97; -.
DR STRING; 1068978.AMETH_2379; -.
DR KEGG; amq:AMETH_2379; -.
DR PATRIC; fig|1068978.7.peg.2537; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_5_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd12119; ttLC_FACS_AlkK_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF11; MEDIUM-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AIJ22471.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000062973}.
FT DOMAIN 23..398
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 448..523
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 555 AA; 59929 MW; 4446E0D88B64048C CRC64;
MLGLMQDHPL SLPHVFRRVE RLFGHKTVVS GRIGGESTTT WAQVCARARR LAAALDELGV
PAGARVGTFA WNSHRHVELY LAVPCTGRVL HTINHRLFGE QISYIVSDAA DDVLFVDRSI
LPAVWPLVGT FTTVRAVVVM DDGSDAEIPD DDRVFDYEEL LARAGDTGRE FTVDDENTAA
ALCYTSGTTG DPKGVLYSHR SVVLHAALLL MVDTFGICER DVVMPIVPMF HVNAWGLPYA
AMLCGADLVL PGPAMSPPEL AGMLARHRVT FGAAVATIWR GLVPLLGEHD FSAVRQIVSG
GGAVDEALTR AYQDAIGLPL TNAWGMTETS PVVTTSRIAT VHDDFPDEQR RALLATPGPA
VPLTEVRIIG DDGREAPWDG RTPGELQAAG PTIAAAYFGK RDGADAFTGD GWLRTGDVAT
IDRHGYVRIV DRTKDLVKSG GEWISSVELE NAIMEHPGVA EAAVIGVPDD KWGERPLACV
VPAAGATLTA EEVRDHLRGR VASWWLPDEV FFCDEIPKTA TGKFAKQRLR SQIETARAGS
GCYTNRDTVA RRSNG
//
