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Database: UniProt
Entry: A0A076NL34_9CORY
LinkDB: A0A076NL34_9CORY
Original site: A0A076NL34_9CORY 
ID   A0A076NL34_9CORY        Unreviewed;       530 AA.
AC   A0A076NL34;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-SEP-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=CIMIT_00005 {ECO:0000313|EMBL:AIJ32525.1};
OS   Corynebacterium imitans.
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=156978 {ECO:0000313|EMBL:AIJ32525.1, ECO:0000313|Proteomes:UP000028780};
RN   [1] {ECO:0000313|EMBL:AIJ32525.1, ECO:0000313|Proteomes:UP000028780}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44264 {ECO:0000313|EMBL:AIJ32525.1,
RC   ECO:0000313|Proteomes:UP000028780};
RA   Mollmann S., Albersmeier A., Ruckert C., Tauch A.;
RT   "Complete genome sequence of Corynebacterium imitans DSM 44264,
RT   isolated from a five-month-old boy with suspected pharyngeal
RT   diphtheria.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP009211; AIJ32525.1; -; Genomic_DNA.
DR   EnsemblBacteria; AIJ32525; AIJ32525; CIMIT_00005.
DR   KEGG; cii:CIMIT_00005; -.
DR   KO; K02313; -.
DR   Proteomes; UP000028780; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028780};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028780}.
FT   DOMAIN      221    349       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      433    502       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     229    236       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   530 AA;  58650 MW;  6A7F8522C5E8107C CRC64;
     MAEQHVESLW RDIVTELLQL SERPDSSVPQ LTYQQRSYLQ LVKPIMLVDG YAVLSAPHAA
     AKTVVEESLA PHITSLLASH MGTPFALAVS VAPTPPPAPA APAEAPTSVP EEFTPEPVQQ
     PAQPPAQPPV QPVSQPRPDT TAPGEQIPMS LDELAQMHAK QQPAQGHPTV PRRIPREKPA
     HDPDRSTSLN PNYTFENFVT GSSNRFANGA ALAVAETPAR AYNPLFIWGG SGLGKTHLLH
     AAGNYAQVLQ PNLRVKYVSS EEFTNDYINS VRDDRQESFK RRYRDLDILM VDDIQFLQGK
     EGTQEEFFHT FNALHQADKQ IILSSDRPPK QLTTLEDRLR TRFEGGLITD VQPPDLETRI
     AILMKKAAAD GTVVDDAVFE LIASHFEASI RELEGAFIRV SAYSSLSNEP ITLENARAAL
     RDILPDEADV KLTADTIKDA AAEYFSLTLE QLTGAGKARQ VAHARQIAMY LCRELTDLSL
     PKIGDEFGGK DHTTVMYADR KIRKEMTETR STYDEIQELT QIIKNKARQG
//
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