ID A0A077DG91_9BURK Unreviewed; 619 AA.
AC A0A077DG91;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=IX83_03490 {ECO:0000313|EMBL:AIL32492.1};
OS Basilea psittacipulmonis DSM 24701.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Basilea.
OX NCBI_TaxID=1072685 {ECO:0000313|EMBL:AIL32492.1, ECO:0000313|Proteomes:UP000028945};
RN [1] {ECO:0000313|EMBL:AIL32492.1, ECO:0000313|Proteomes:UP000028945}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24701 {ECO:0000313|EMBL:AIL32492.1,
RC ECO:0000313|Proteomes:UP000028945};
RX PubMed=24581117; DOI=10.1186/1471-2164-15-169;
RA Whiteson K.L., Hernandez D., Lazarevic V., Gaia N., Farinelli L.,
RA Francois P., Pilo P., Frey J., Schrenzel J.;
RT "A genomic perspective on a new bacterial genus and species from the
RT Alcaligenaceae family, Basilea psittacipulmonis.";
RL BMC Genomics 15:169-169(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP009238; AIL32492.1; -; Genomic_DNA.
DR RefSeq; WP_038499183.1; NZ_CP009238.1.
DR AlphaFoldDB; A0A077DG91; -.
DR STRING; 1072685.IX83_03490; -.
DR KEGG; bpsi:IX83_03490; -.
DR eggNOG; COG0210; Bacteria.
DR HOGENOM; CLU_006494_1_1_4; -.
DR OrthoDB; 5298826at2; -.
DR Proteomes; UP000028945; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000028945}.
FT DOMAIN 1..419
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 22..29
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 619 AA; 73569 MW; BBDB0E55A0B1BDD9 CRC64;
MRLNEEQREA AYAEDQNVLV LAGAGTGKTT VLIERLLYLR KQNRKVLFLA FSAEVAREIR
EKIAKQNIEA DVFTFHALSL HLCKTLDDSR DFQVTTSSDW EQVSDITWQV CQELCEDDTQ
WAEFLDFLEH EEIYYSLHGT AWLHQRGLGL LSFRQDGFQS IADLRVAIAL ERLKCQYVYR
PLIKPYPHTA YASFYLPEHD YYLNVMQDNG EYPLTSEIFE DLSLNVLHLH HVDLEAIAEK
KMEHITFPNP YIQCLSAFEG DEEPVFSFHQ RVHQFVQRML DIVPASIEKT LPDSPLWHMQ
YIKRLVDRIA QKVILNWTET NKITFFQMIE EAKKLIINTQ YQADWDDILV DEFQDLTDQQ
YTLLSTLRKN KPNLNLFCVG DDWQAIYEFA GSNLAYILKF EQYFGPVSLY YLTQTYRFHE
SISYIAQEFL LKNPKQINKN LRARKKTKGE CIRVFAHHIP MKNMMKYRKC DETVMFLARC
HADLPHAKIQ EKWMEKYPFV RFMTMHASKG LEADHVVLLN LVKGNMPLQR DYINDYFLDW
IHPKTPLDFP FEDERRLFYV ALTRAKKYLW LQTDWHQPSN FLMELLALPQ SERHIRFYGH
QVKNYYTFQK LKRRSSPVY
//
