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Database: UniProt
Entry: A0A077HHT5_9CORY
LinkDB: A0A077HHT5_9CORY
Original site: A0A077HHT5_9CORY 
ID   A0A077HHT5_9CORY        Unreviewed;       512 AA.
AC   A0A077HHT5;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 26.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=CUREI_00005 {ECO:0000313|EMBL:AIL95926.1};
OS   Corynebacterium ureicelerivorans.
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=401472 {ECO:0000313|EMBL:AIL95926.1, ECO:0000313|Proteomes:UP000028939};
RN   [1] {ECO:0000313|EMBL:AIL95926.1, ECO:0000313|Proteomes:UP000028939}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMMIB RIV-2301 {ECO:0000313|EMBL:AIL95926.1,
RC   ECO:0000313|Proteomes:UP000028939};
RA   Tippelt A., Albersmeier A., Brinkrolf K., Ruckert C., Tauch A.;
RT   "Complete genome sequence of Corynebacterium ureicelerivorans DSM
RT   45051, a lipophilic and urea-splitting isolate from a blood culture of
RT   a septicaemia patient.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP009215; AIL95926.1; -; Genomic_DNA.
DR   RefSeq; WP_051952363.1; NZ_CP009215.1.
DR   EnsemblBacteria; AIL95926; AIL95926; CUREI_00005.
DR   KEGG; cuv:CUREI_00005; -.
DR   KO; K02313; -.
DR   Proteomes; UP000028939; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028939};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028939}.
FT   DOMAIN      201    329       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      413    482       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     209    216       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   512 AA;  56734 MW;  D8E301766D642505 CRC64;
     MADQHLADLW HGVVDELLRL SEQATSSVPT LTPQQRAYLR LMKPVVLVDG YALLSAPHQA
     AKNVVEESLA PHITAVLSSH TGQPYNLAVS VAAPEPEPTP APQTSWQPTQ SNVEAPGVGE
     QIPMGLDELA QMHAAQVAGR RREANAHPTV DRRIPREKPA HDPDREASLN PKYTFENFVI
     GSSNRFANGA AVAVAENPAK AYNPLFIWGG SGLGKTHLLH AAGNYAGVLQ PGLRIKYVSS
     EEFTNDYINS VRDDRQESFK RRYRNLDILM VDDIQFLEGK EGTQEEFFHT FNALHQANKQ
     IILSSDRPPK QLTTLEDRLR TRFEGGLITD VQPPDLETRI AILMKKAAAD GTQVDHQVLE
     LIASQFESSI RELEGALIRV SAYSSLINEP ITMDVAQVAL RDILPDEGDV NITATAIKDA
     AAEYFQVSLE QLTGAGKTRQ VAHARQIAMY LCRELTDLSL PKIGDEFGGK DHTTVMYADR
     KIRKEMTENR GTYDEIQELT QVVKNRARAR GR
//
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