ID A0A077M7B7_9MICO Unreviewed; 201 AA.
AC A0A077M7B7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=nicotinamidase {ECO:0000256|ARBA:ARBA00039017};
DE EC=3.5.1.19 {ECO:0000256|ARBA:ARBA00039017};
DE AltName: Full=Nicotinamide deamidase {ECO:0000256|ARBA:ARBA00043224};
GN Name=pncA {ECO:0000313|EMBL:CCI51700.1};
GN ORFNames=BN13_1170004 {ECO:0000313|EMBL:CCI51700.1};
OS Tetrasphaera jenkinsii Ben 74.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Tetrasphaera.
OX NCBI_TaxID=1193518 {ECO:0000313|EMBL:CCI51700.1, ECO:0000313|Proteomes:UP000035720};
RN [1] {ECO:0000313|EMBL:CCI51700.1, ECO:0000313|Proteomes:UP000035720}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ben 74 {ECO:0000313|EMBL:CCI51700.1,
RC ECO:0000313|Proteomes:UP000035720};
RX PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA Nielsen K.L., Nielsen P.H.;
RT "A metabolic model for members of the genus Tetrasphaera involved in
RT enhanced biological phosphorus removal.";
RL ISME J. 7:543-554(2013).
CC -!- PATHWAY: Cofactor biosynthesis; nicotinate biosynthesis; nicotinate
CC from nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00037900}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI51700.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAJC01000021; CCI51700.1; -; Genomic_DNA.
DR RefSeq; WP_048548077.1; NZ_HF571038.1.
DR AlphaFoldDB; A0A077M7B7; -.
DR STRING; 1193518.BN13_1170004; -.
DR OrthoDB; 9791276at2; -.
DR Proteomes; UP000035720; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008936; F:nicotinamidase activity; IEA:UniProtKB-EC.
DR GO; GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR11080:SF2; LD05707P; 1.
DR PANTHER; PTHR11080; PYRAZINAMIDASE/NICOTINAMIDASE; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CCI51700.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Reference proteome {ECO:0000313|Proteomes:UP000035720}.
FT DOMAIN 4..192
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 201 AA; 20146 MW; 1EEA615DDFD41982 CRC64;
MSRALLIVDI QPDFCEGGSL PVTGGNAVAA AVARYVDEAG ADYALIATSQ DWHNPDSTNG
GHFAAEPDYR TTWPAHCVAG TPGAELHSDL AEALTKATTT VVGVHKGQDA PAYSAFEGTA
SDGRALAQLL TDAGVTEVDV VGIATDHCVR ATALDALAAG LDTTLLAGLH AGVAADTTDA
ALTELADAGA DVGRPLAPAT A
//
