ID   A0A077ZKK4_TRITR        Unreviewed;      1398 AA.
AC   A0A077ZKK4;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=TTRE_0000865401 {ECO:0000313|EMBL:CDW60289.1};
OS   Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichuridae; Trichuris.
OX   NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW60289.1};
RN   [1] {ECO:0000313|EMBL:CDW60289.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Aslett M.;
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDW60289.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA   Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA   Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT   "The whipworm genome and dual-species transcriptomics of an intimate host-
RT   pathogen interaction.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; HG806997; CDW60289.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A077ZKK4; -.
DR   STRING; 36087.A0A077ZKK4; -.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1398 AA;  160634 MW;  470EE9AB6C190AE4 CRC64;
     MAASARSIDY FPAELQMRFI CRQNSRDGVA LCGMLKEYLR PVEKSLDVSA HVSTLDEGNS
     ENDTYKLFVR MVCESAGKRE FENLLLDFFS IWTSLRKTKG SENSKKEPLF FELCQDAAFR
     CPFDPRHSWK YIADINLGYF LGIGEFFSVC AFDRKAYDVF FCDFEHDIRR MEIVFAEKRS
     KSTHDKYTTR YKMSVSYKAL NYVTVDYDQH WADIYLTVKY PPLLWKWKHF GGHSSHNEAI
     VSLPFCCRET FGSCSVIMLR LKTTQAIEDE MLWALICRLK RRARVPVYFG RVTIEPLTKL
     PDHEMTEASW NFDCQYYWCA LKSRSLSVAS QMDSNFADQL LTAFERNQKA TEHALSYLLS
     LVDQLQEIFL PSSFKKYFDK YDSLNLAELE KMERSESDDG MVRVRKVVFT PTRTLLTVPD
     TMLSNRVIRR FGAEWALRVS FRSDNGGRMR AFSFNSDDID EVLRRPLRDG LTIGDRHYEF
     LGWSNSQLRD GGCYFYCRTA QGECVSDIRK WMGNFDGIGN VPKLMSRMGQ CFTQSLSAVE
     IPYPIGSSEV PIQEDHFSQL YGEKVFCFSD GVGQISVQLA EEVSEKLNLS PVPSAFQIRF
     AGCKGMLAVN PRLPEVQKMV FRESMLKFRT ETSNVLEIVK TSQPCPVNLN RPLILILDQV
     AECENPLVRQ NMQRRINELL NEQLYGLSDM LLLESCASRE LPKSVQLGIN FKSLSEVGIR
     MTNEVFFRNM MLSIYSSKVK EQLLKLKIDV PTHLGRTLFG ILDETRTLAP DEVFIQISTD
     INEPGKNLKV IEGAVMVTKS PCIVPGDVRI LNAVKTDLLM HLRDVIVFPR IGLRPVMDQM
     AGSDLDGDEY LAFWDTDLMF TGNYDPLSFP KTDVPKFEGE ITTEAMIDFF ITYLCSDSIG
     TIATSHMVAA DRFGIFSDVP MQLANKHTMA VDFPKTGIVP EKLTCEERIE KYPDYLWFGS
     RPTYRSKWLP GPMTRRVRSV IDIIDLSSVR SFDASVDFDL AYGNWKDFAA NAARTYSKYR
     QLVFSLLSEY GIDNEFQLFS GHFTDLKGRL SRGERDDYSL FTTERIVQMR LKRLIAKFRN
     QFAREFEVDS SELATNEKAL AKASAWYMVA YRDRTVVNSR SAFSFGWLMW DLLAVIKERR
     VKNPKAPCNP VMDHLEQLIE KTSVRKFEHL KESLSKCGVT SNYNEGIKHV LYIYLEWCLR
     SHLVTEADSK EALFTFVGTF DRFLKDLKSS PQLPFDMITT DETGKFVISF LSKGQLLMKF
     FKYLGTQAGD TNRSQANEHA DALRALVDLA FKAYHKAALS GDFSSFYLEQ PKRVESDAEE
     MDPITFLPTP TIEQLYGMEH VCEKLRIWSG VTDLRYREKG SGYYLISAIG TLEARFRLCD
     LLTCDDLESA LKYDTCPF
//