ID A0A078AQJ4_STYLE Unreviewed; 807 AA.
AC A0A078AQJ4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=acylaminoacyl-peptidase {ECO:0000256|ARBA:ARBA00012917};
DE EC=3.4.19.1 {ECO:0000256|ARBA:ARBA00012917};
GN Name=Contig17416.g18526 {ECO:0000313|EMBL:CDW84705.1};
GN ORFNames=STYLEM_13771 {ECO:0000313|EMBL:CDW84705.1};
OS Stylonychia lemnae (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Stylonychia.
OX NCBI_TaxID=5949 {ECO:0000313|EMBL:CDW84705.1, ECO:0000313|Proteomes:UP000039865};
RN [1] {ECO:0000313|EMBL:CDW84705.1, ECO:0000313|Proteomes:UP000039865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=130c {ECO:0000313|EMBL:CDW84705.1,
RC ECO:0000313|Proteomes:UP000039865};
RA Swart Estienne;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Cleavage of an N-acetyl or N-formyl amino acid from the N-
CC terminus of a polypeptide.; EC=3.4.19.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000721};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CCKQ01013078; CDW84705.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078AQJ4; -.
DR EnsemblProtists; CDW84705; CDW84705; STYLEM_13771.
DR InParanoid; A0A078AQJ4; -.
DR OMA; NLLDFQW; -.
DR OrthoDB; 180425at2759; -.
DR Proteomes; UP000039865; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR045550; AARE_N.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR PANTHER; PTHR42776:SF4; ACYLAMINO-ACID-RELEASING ENZYME; 1.
DR PANTHER; PTHR42776; SERINE PEPTIDASE S9 FAMILY MEMBER; 1.
DR Pfam; PF19283; APEH_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000039865}.
FT DOMAIN 49..291
FT /note="Acylamino-acid-releasing enzyme N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19283"
FT DOMAIN 558..774
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 780..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 807 AA; 93222 MW; A9C07A1041B06C9E CRC64;
MQTCKTRRDA LCKVFEAVSK PLPAYGGAAI SHLTDARESG KYVVKIVKEQ FDLKRIQKLG
FQSQYLVDKQ RNEVSRLTSV PLDAAASSLL CLTQSPTNDS LQVRFRKGEK NDKDIFVEVW
DDSVRGFISS RKITDKCTRI YNDAIFGGIS WSRDNNRITF IGEKPEPAAY KNYWEDEQPI
AAAKVEEEKK QEEQKEEKKK EDTFLDQKYL LQEDFGETLV GKKIPVIFIF NIKENTFEEV
QGIESGLYPA YPMFDEQSKG IVFVGYRLPT KKIGMNFCLN KDTKLYYIKE IIADKAKLDS
KPVGYVTCLN STEFASFMPK FSRDYSRILY FGAKEKFLSH SGNYQLRFLN WPVAEGVEST
LVLDKRGEYP SETDEYAGLF GYNQSYIHAG FLGDSQRYAI FQSTLCGQER IYLADLDEKK
VRWLNFLGKD HENRMNGEYE FMRVLDDHLV VKHSQCDMPP HIYSVLFKNI HTESLDQLVD
LNNLQINLLE KVTFEESRSE LEGQIGKFIQ NISRETIRLE NGAEGYFIRN NQLPQDTKHP
LVVMVHGGPF GCYPQDMFSR MRIQLILQGY QLLVINFRGS TGYGEDFLNS LLGHISEYDR
EDCGNLTKLA LDKYKDQIDP ERVGIFGGSH GGYLTGWLIG HPDTKDIFKA AVLWNPVINM
SYMVAQTDIP DWIYNCSLNQ EHRYELTSEE NKEFFDKSPI SVVNNVQAAA LLLIGHQDFR
VPPNQAYHYY HILKSQGKKV KLYKYPEDGH AILGTETGLD AELNIYFWFD EIFQDVVTKR
QQQQQQQQDQ EQQEQTQVES KQEEQQQ
//
