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Database: UniProt
Entry: A0A078B352_STYLE
LinkDB: A0A078B352_STYLE
Original site: A0A078B352_STYLE 
ID   A0A078B352_STYLE        Unreviewed;       869 AA.
AC   A0A078B352;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   15-FEB-2017, entry version 12.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   Name=Contig10881.g11624 {ECO:0000313|EMBL:CDW87677.1};
GN   ORFNames=STYLEM_16789 {ECO:0000313|EMBL:CDW87677.1};
OS   Stylonychia lemnae (Ciliate).
OC   Eukaryota; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae;
OC   Stylonychia.
OX   NCBI_TaxID=5949 {ECO:0000313|EMBL:CDW87677.1, ECO:0000313|Proteomes:UP000039865};
RN   [1] {ECO:0000313|EMBL:CDW87677.1, ECO:0000313|Proteomes:UP000039865}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=130c {ECO:0000313|EMBL:CDW87677.1,
RC   ECO:0000313|Proteomes:UP000039865};
RA   Swart Estienne;
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; CCKQ01015832; CDW87677.1; -; Genomic_DNA.
DR   EnsemblProtists; CDW87677; CDW87677; STYLEM_16789.
DR   Proteomes; UP000039865; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000039865};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000039865};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    466    487       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    493    512       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    566    587       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    599    619       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    655    676       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   869 AA;  100531 MW;  A41B4252EAC7C115 CRC64;
     MGILRSEDMF LFKFVVQKDN VWEIINNLGR TKSVHFIDMN RNEQSFKLPY TDMIKRCEET
     ERRLIYRVKL ITPQTLQHLE QSIDSIGENK RKAMSVLFED IENEIREKEQ FVISQNEKIK
     SMIDILNMQI EYQTVLEKAD KIIHGKIRSR GSSLQGIQNN DFEANASQPF GRSKINYSNE
     EVKEEEIQLS GRSSGGSNRL EQSFREVSIR YVAGTIENTE VERFKKVLFR SLRGKVLSYF
     DESNVILNDF QGKSIRKCVY VLVFEEGSHF IDKVTRICEA FSAKRYSLPE GGHTDKSAFH
     RKIQKIAKNI TDTQQMLKFT RQQMHNYLEG INQTQGVAFS VQEVYKLFIK KEKSVYLVLN
     QLKTERNLCF GFFWSNLAKH QLMNTIYKSG HEDMNLQQKI QIEDFNFSKI KPPTYIQTNE
     FTYIFQEIIN TYGVPTYKEI NPAIFACVSF PFLFGVMFGD VGHGSLLLFI GTVLCLFNNC
     IGGNFPAMKP VLQLRYVVFL MGLFGMFAGF IYNDMMSISL NVYGSCYNTD TGKYLGNDCI
     YPIGLDPIWS LSKNELSFQN SLKMKISVIL GVMQMSLGVV LKAFNAVFFK NSLDFYHEFI
     PQILLLWSLF GYMDSLIVIK WLTNYQGDEH SAPSIITTMI NLALNGGHVE GRPFIGSYGA
     NKAIMIALIC VPWMLFVKPL KLRKEHEHKD QEEQNNHYQD QRKNQSPQKK INQNSNNHFS
     NLASDQMTIA DYGNNEDIIL DLMGQGGHQN HEFSEIFIHQ LIETIEFVLG TISNTASYLR
     LWALSLAHSQ LSKVFFEHSL LQGIIDASPV KIFVCYFIWA TATFGVLMCM DVLECFLHTL
     RLHWVEFQNK FYKGQGYKFQ PFTYDILFK
//
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