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Database: UniProt
Entry: A0A078FN70_BRANA
LinkDB: A0A078FN70_BRANA
Original site: A0A078FN70_BRANA 
ID   A0A078FN70_BRANA        Unreviewed;       819 AA.
AC   A0A078FN70;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   02-NOV-2016, entry version 9.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   Name=BnaA04g12160D {ECO:0000313|EMBL:CDY15895.1};
GN   ORFNames=GSBRNA2T00090255001 {ECO:0000313|EMBL:CDY15895.1};
OS   Brassica napus (Rape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae;
OC   Brassica.
OX   NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY15895.1, ECO:0000313|Proteomes:UP000028999};
RN   [1] {ECO:0000313|EMBL:CDY15895.1, ECO:0000313|Proteomes:UP000028999}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX   PubMed=25146293; DOI=10.1126/science.1253435;
RA   Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X.,
RA   Chiquet J., Belcram H., Tong C., Samans B., Correa M., Da Silva C.,
RA   Just J., Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P.,
RA   Noel B., Labadie K., Alberti A., Charles M., Arnaud D., Guo H.,
RA   Daviaud C., Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H.,
RA   Tack D., Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G.,
RA   Renault V., Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H.,
RA   Chalabi S., Hu Q., Fan C., Tollenaere R., Lu Y., Battail C., Shen J.,
RA   Sidebottom C.H., Wang X., Canaguier A., Chauveau A., Berard A.,
RA   Deniot G., Guan M., Liu Z., Sun F., Lim Y.P., Lyons E., Town C.D.,
RA   Bancroft I., Wang X., Meng J., Ma J., Pires J.C., King G.J.,
RA   Brunel D., Delourme R., Renard M., Aury J.M., Adams K.L., Batley J.,
RA   Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W., Sharpe A.G.,
RA   Paterson A.H., Guan C., Wincker P.;
RT   "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT   Brassica napus oilseed genome.";
RL   Science 345:950-953(2014).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; LK032059; CDY15895.1; -; Genomic_DNA.
DR   EnsemblPlants; CDY15895; CDY15895; GSBRNA2T00090255001.
DR   Gramene; CDY15895; CDY15895; GSBRNA2T00090255001.
DR   Proteomes; UP000028999; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028999};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028999};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    423    447       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    468    485       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    548    566       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    578    601       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    637    655       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    756    777       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED      101    135       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   819 AA;  92798 MW;  30028CA1AF93318F CRC64;
     MAEIGGGCCP PMDLMRSEPM QLVQVIVPME SAHLTVSYLG DLGLVQFKDL NSDKSPFQRT
     YAAQIKRCGE MARKLRFFKD QMSKAGVSPK EFLGKDVDID LDDVEVKLGE LEAELSEINA
     NNDKLQRSYN ELMEYKLVLE KAGEFFASAH RSATTQQSEI ESQQQVGEDA LEAPLLQEEK
     SVDPTKQVKL GFLTGLVPRE KSMVFERILF RATRGNIFIR QSVIEESVVD PSSGEKAEKN
     VFVVFYSGER AKSKILKICE AFGANRYPFS EELSKQAQMM TEVTGRLAEL KTTISAGLDH
     RKILLETIGD KFEQWNLKVR KEKAIYHTLN MLSLDVTKKC LVGEGWSPVF ATPEIQKALE
     RAAVDSNSQV GSIFQVLRTK EMPPTFFRTN KFTTAFQEIV DAYGVAIYQE ANPTVFTIVT
     FPFLFAVMFG DWGHGICLLI ATMYLVLKEK KLSSQKLGDI MEMAFGGRYV ILMMSLFSIY
     TGLIYNEFFS IPFPLFAPSA YECRDASCSE ATTIGLIKTR DTYPFGVDPV WHGTRSELPF
     LNSLKMKMSI LLGVAQMNLG IIMSFCNAKF FKSAVNIWFQ FVPQMIFLNC LFGYLSALII
     IKWCTGSQAD LYHVMIYMFL SPMEDLGENQ LFPHQKTVQL TFLFLALISV PWMLLPKPFI
     LKKQHEARHQ GQSYAQLEET DESLQVETNG GPHGHEEFEF SEIFVHQLIH TIEFVLGAVS
     NTASYLRLWA LSLAHSELSS VFYEKVLLMA WGFNNFLILI VGILVFIFAT VGVLLVMETL
     SAFLHALRLH WVEYQNKFYE GDGYKFAPFT FTLLGNEDE
//
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