ID A0A078IT64_BRANA Unreviewed; 1008 AA.
AC A0A078IT64;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=BnaCnng22930D protein {ECO:0000313|EMBL:CDY52614.1};
GN Name=BnaCnng22930D {ECO:0000313|EMBL:CDY52614.1};
GN ORFNames=GSBRNA2T00007396001 {ECO:0000313|EMBL:CDY52614.1};
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY52614.1, ECO:0000313|Proteomes:UP000028999};
RN [1] {ECO:0000313|EMBL:CDY52614.1, ECO:0000313|Proteomes:UP000028999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX PubMed=25146293; DOI=10.1126/science.1253435;
RA Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X., Chiquet J.,
RA Belcram H., Tong C., Samans B., Correa M., Da Silva C., Just J.,
RA Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P., Noel B.,
RA Labadie K., Alberti A., Charles M., Arnaud D., Guo H., Daviaud C.,
RA Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H., Tack D.,
RA Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G., Renault V.,
RA Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H., Chalabi S., Hu Q.,
RA Fan C., Tollenaere R., Lu Y., Battail C., Shen J., Sidebottom C.H.,
RA Wang X., Canaguier A., Chauveau A., Berard A., Deniot G., Guan M., Liu Z.,
RA Sun F., Lim Y.P., Lyons E., Town C.D., Bancroft I., Wang X., Meng J.,
RA Ma J., Pires J.C., King G.J., Brunel D., Delourme R., Renard M., Aury J.M.,
RA Adams K.L., Batley J., Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W.,
RA Sharpe A.G., Paterson A.H., Guan C., Wincker P.;
RT "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT Brassica napus oilseed genome.";
RL Science 345:950-953(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the retinoblastoma protein (RB) family.
CC {ECO:0000256|ARBA:ARBA00009475}.
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DR EMBL; LK033108; CDY52614.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078IT64; -.
DR STRING; 3708.A0A078IT64; -.
DR PaxDb; 3708-A0A078IT64; -.
DR EnsemblPlants; CDY52614; CDY52614; GSBRNA2T00007396001.
DR Gramene; CDY52614; CDY52614; GSBRNA2T00007396001.
DR OMA; NDNDAQC; -.
DR Proteomes; UP000028999; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20601; CYCLIN_AtRBR_like; 1.
DR Gene3D; 1.10.472.140; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR002720; RB_A.
DR InterPro; IPR002719; RB_B.
DR InterPro; IPR028309; RB_fam.
DR InterPro; IPR024599; RB_N.
DR PANTHER; PTHR13742; RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED; 1.
DR PANTHER; PTHR13742:SF31; RETINOBLASTOMA-RELATED PROTEIN; 1.
DR Pfam; PF11934; DUF3452; 1.
DR Pfam; PF01858; RB_A; 1.
DR Pfam; PF01857; RB_B; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SMART; SM01367; DUF3452; 1.
DR SMART; SM01368; RB_A; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000028999};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 84..222
FT /note="Retinoblastoma-associated protein N-terminal"
FT /evidence="ECO:0000259|SMART:SM01367"
FT DOMAIN 396..597
FT /note="Retinoblastoma-associated protein A-box"
FT /evidence="ECO:0000259|SMART:SM01368"
FT DOMAIN 731..849
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 969..1008
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 111881 MW; 210A3684D2800B58 CRC64;
MEEVQPPVTP PIDPNGKRSE ATLFDLCEKV LSLEGSVCDE ALKLFSETKR ILSANMANIG
SGTREEVERF WFAFILYSVK MLLTSVSGDN GFNLCQILRA LKLNIVDFFK ELPQFVVKAG
PVLCELYGAD WENRLQAKEL QANFVHLSLL SKYYKRGYRE FFLTYDANAE MTSANSASYL
PDSYRFGWLL FLALRNHAFS RFKDLVTCTN GLVSVLAILI IHVPCRFRNF SIQDSSRFVK
KGDKDVDLVA SLCKIYDASE DELRKIMEKA NNLIETILKK KPSPASACKT DTLDNINPDG
LTYFEDLLDE TSISTSLTTL EKDYDETVCN KGELDERVFI NEEDSLLGSG SLSAGAVNIT
GAKRKIDSLS SPARTFISPL SPHKSPAAAK TTVTATPVST AMTTAKWLRT VICPLPPKPS
PGLELFLKSC DRDITNDVTR RAHVILEAIF PNSSLGDQCA GGSLQPVNLM DDIWAQQRRL
EAVKLYYRVL EAMCKAEAQI LHVNNLNSLL TNERFHRCML ACSAELVLAT HKSITMLFPA
VLERTGITAF DLSKVIESFI RHEDSLPREL RRHLNSLEER LLESMVWERG SSMYNSLIVA
KAPLALEINR LGLLAEPMPS LDAIAALINF SEGSSNHVQK PEACPGQNGD IKSPKRLCTD
YRSILVERSS FASPVKDRLL ALGNVKSKTL PPPLQSAFAT PTRPNPGGGG ETCAETGINI
FFTKINKLAA VRINGMVERL QLSQQIRESV YRLFQRVLAQ RTSLLFNRHI DQIILCCFYG
VAKISQMSLT FREIIYNYRK QPQCKPLVFR SVFVDSSQGR RQGRVGPDHV DIITFYNDVF
IPAVKPLLVE IVPVKKDQAM EANTNPEGHC PGSPKVSVFP SVPDMSPKKV SAVHNVYVSP
LRGSKMDALI SHSSKSYYAC VGESTHAYQS PSKDLSAINN RLNNNNSSNR KRTLKFDVEA
GLVSDSMVGN SLSLQNQNQN ETDASNQNQN GSDASSSGGA PFKTEPQD
//
