ID   A0A078KM45_9FIRM        Unreviewed;       869 AA.
AC   A0A078KM45;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CCDG5_0454 {ECO:0000313|EMBL:CDZ23592.1};
OS   [Clostridium] cellulosi.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=29343 {ECO:0000313|EMBL:CDZ23592.1, ECO:0000313|Proteomes:UP000032431};
RN   [1] {ECO:0000313|Proteomes:UP000032431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG5 {ECO:0000313|Proteomes:UP000032431};
RA   Wibberg D.;
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; LM995447; CDZ23592.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A078KM45; -.
DR   STRING; 29343.CCDG5_0454; -.
DR   KEGG; ccel:CCDG5_0454; -.
DR   PATRIC; fig|29343.3.peg.475; -.
DR   HOGENOM; CLU_330025_0_0_9; -.
DR   OrthoDB; 1862723at2; -.
DR   Proteomes; UP000032431; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.20.120.1530; -; 3.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF18947; HAMP_2; 3.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 3.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032431};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        43..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          388..440
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          580..809
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          824..869
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        853..869
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   869 AA;  95044 MW;  A87B78CA6A221D6E CRC64;
     MKKENIRQNK RKIALPLLVA YILAFCAGLF GACAITGPQS SKIIFGVLFF VFFIALLITV
     TLTVRKTNNI FKSVKKLLDD GKYYKAVLDC IPFPVHAVDN NMKWKFVNKA FEKSLVKSGK
     IADRKSAYGM VCSTAGANIC NNEKCGIKQL QKGVHESYFE WSGNKCRLNA AAIVGENGEK
     LGYVETVTNL TKLIENEEYY KKAIANLMSN LEKLSRGDLD LDLSVPEANS NTQESRETFV
     MINESLGRVK ESLELLTNDA AYLRAAAVEG RLDTRVDASG HSGVYQKIIS GIDDTLEAIV
     KPVKFTTEYI LKLANGEDLE EIENTYSGDY AVLMNSLNSV RESLYTLLDE SIKLLEAGRE
     GNLTARADTS KFKGGYAKVI AGINGMFEAF ATPLNEANEI LALMANNDFT RGMDKDYNGE
     FGKLAESVNK LRETFLIIEE LLIEISNGDL SQLEEIMKMP KRSENDRLRP AFIEMMKSVK
     QLVDEANMLA ESAANGKLSV RGNAAGLKGE YGEVVAHINR MIEAVEKPFN DLVFVLEKWT
     EGDLTAEIDK EYIGDYLRIK NAVNTTGEKF RQMLNSINEA ASQVASGSKE IASGSQNLSR
     GTTEQASSIE ELTAAISEIA EQTKNNAKNA ENAKSLSLEV QKEAIEGNEK MKSMQEAMRG
     ISDSSANIAK IIKVIDDIAF QTNILSLNAA VEAARAGQAG KGFAVVAQEV RTLASRSATA
     AKETTQLIED SSKRVEIGAK IVDETAAEFE KIMQSIEKTT KLVGEISEAS AKQATGITQI
     DKGIEQVSTV VQTNSATAEE SAAASEQLSA QAQALRDMVS QFKLGKSSEE PVEKSNVKAE
     RNAAPAIQEK ETQPKIVLDD KPQGDYGKY
//