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Database: UniProt
Entry: A0A080JWZ3_9NEIS
LinkDB: A0A080JWZ3_9NEIS
Original site: A0A080JWZ3_9NEIS 
ID   A0A080JWZ3_9NEIS        Unreviewed;       531 AA.
AC   A0A080JWZ3;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=SASC598O02_013760 {ECO:0000313|EMBL:KES09495.1};
OS   Snodgrassella alvi SCGC AB-598-O02.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
OC   Neisseriaceae; Snodgrassella.
OX   NCBI_TaxID=1443103 {ECO:0000313|EMBL:KES09495.1, ECO:0000313|Proteomes:UP000028323};
RN   [1] {ECO:0000313|Proteomes:UP000028323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=25210772; DOI=10.1371/journal.pgen.1004596;
RA   Engel P., Stepanauskas R., Moran N.;
RT   "Hidden diversity in honey bee gut symbionts detected by single-cell
RT   genomics.";
RL   PLoS Genet. 10:e1004596-e1004596(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KES09495.1}.
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DR   EMBL; JAIL01000257; KES09495.1; -; Genomic_DNA.
DR   EnsemblBacteria; KES09495; KES09495; SASC598O02_013760.
DR   PATRIC; fig|1443103.3.peg.1208; -.
DR   Proteomes; UP000028323; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028323};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028323}.
FT   DOMAIN      228    358       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      439    508       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     236    243       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   531 AA;  59445 MW;  B75E134485ACB6C6 CRC64;
     MTFTEFWPQC LLHLQQNLPA QQYQMWIAPL TVGEENGKWV LFARNTFTFN HVRDRFWSAI
     EEACLTINAD SKLPLILKIG QGQLLPAAAK SDNIPAQTKP ANEPAKVNDV VATIASPQNS
     KPPVELKSTV SAQDIIAKRL RNQSSKTVSN TGQSEDHTVK GKQPKTEKSA TAALSSENEN
     ASEQAKKNRY LDTNLNPEHT FATLVQGKGN RLAHAAALSI AENPGNSMYN PFFVYGSTGL
     GKTHLVQAIG NQLFTTNPKV KIRYIHADEF IRGIMNAFHA KSFDAMRLQY QQVDLLIMDD
     VQFIAGKDRT MEEFFYVYNH LIDEKKQVIL TCDTLPSHID GMDDRLKSRF SWGLSLELEP
     PELEMRVAIL QKKAELAQVK LEDEAAFFIA KHIRSNVREL EGAFKRVVAQ SRFASRPIDV
     GLATEALQDI LAVNHKPMTL EHIQNTVAKF YGITISDMVG KKRTRNLARP RQMAMTLAKE
     LTQLSLPAIG SGFGGRDHTT VMHAVKSITK LRKDDAETAK AYETLMMILR D
//
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